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Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis.
Gardner AI, Haq IJ, Simpson AJ, Becker KA, Gallagher J, Saint-Criq V, Verdon B, Mavin E, Trigg A, Gray MA, Koulman A, McDonnell MJ, Fisher AJ, Kramer EL, Clancy JP, Ward C, Schuchman EH, Gulbins E, Brodlie M. Gardner AI, et al. Among authors: kramer el. Am J Respir Crit Care Med. 2020 Oct 15;202(8):1133-1145. doi: 10.1164/rccm.202001-0180OC. Am J Respir Crit Care Med. 2020. PMID: 32569477 Free PMC article.
TGFβ as a therapeutic target in cystic fibrosis.
Kramer EL, Clancy JP. Kramer EL, et al. Expert Opin Ther Targets. 2018 Feb;22(2):177-189. doi: 10.1080/14728222.2018.1406922. Epub 2017 Dec 13. Expert Opin Ther Targets. 2018. PMID: 29168406 Free PMC article. Review.
Chronic β2AR stimulation limits CFTR activation in human airway epithelia.
Brewington JJ, Backstrom J, Feldman A, Kramer EL, Moncivaiz JD, Ostmann AJ, Zhu X, Lu LJ, Clancy JP. Brewington JJ, et al. Among authors: kramer el. JCI Insight. 2018 Feb 22;3(4):e93029. doi: 10.1172/jci.insight.93029. eCollection 2018 Feb 22. JCI Insight. 2018. PMID: 29467332 Free PMC article.
Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia.
Hudock KM, Collins MS, Imbrogno M, Snowball J, Kramer EL, Brewington JJ, Gollomp K, McCarthy C, Ostmann AJ, Kopras EJ, Davidson CR, Srdiharan A, Arumugam P, Sengupta S, Xu Y, Worthen GS, Trapnell BC, Clancy JP. Hudock KM, et al. Among authors: kramer el. Am J Physiol Lung Cell Mol Physiol. 2020 Jul 1;319(1):L137-L147. doi: 10.1152/ajplung.00144.2019. Epub 2020 Mar 11. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32159969 Free PMC article.
Fibrocyte accumulation in the lungs of cystic fibrosis patients.
Kasam RK, Gajjala PR, Jegga AG, Courtney JA, Randell SH, Kramer EL, Clancy JP, Madala SK. Kasam RK, et al. Among authors: kramer el. J Cyst Fibros. 2020 Sep;19(5):815-822. doi: 10.1016/j.jcf.2020.06.011. Epub 2020 Jun 25. J Cyst Fibros. 2020. PMID: 32593509 Free PMC article.
89 results