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Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology.
Baglietto-Vargas D, Forner S, Cai L, Martini AC, Trujillo-Estrada L, Swarup V, Nguyen MMT, Do Huynh K, Javonillo DI, Tran KM, Phan J, Jiang S, Kramár EA, Nuñez-Diaz C, Balderrama-Gutierrez G, Garcia F, Childs J, Rodriguez-Ortiz CJ, Garcia-Leon JA, Kitazawa M, Shahnawaz M, Matheos DP, Ma X, Da Cunha C, Walls KC, Ager RR, Soto C, Gutierrez A, Moreno-Gonzalez I, Mortazavi A, Tenner AJ, MacGregor GR, Wood M, Green KN, LaFerla FM. Baglietto-Vargas D, et al. Among authors: kramar ea. Nat Commun. 2021 Apr 23;12(1):2421. doi: 10.1038/s41467-021-22624-z. Nat Commun. 2021. PMID: 33893290 Free PMC article.
The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory.
Vogel-Ciernia A, Matheos DP, Barrett RM, Kramár EA, Azzawi S, Chen Y, Magnan CN, Zeller M, Sylvain A, Haettig J, Jia Y, Tran A, Dang R, Post RJ, Chabrier M, Babayan AH, Wu JI, Crabtree GR, Baldi P, Baram TZ, Lynch G, Wood MA. Vogel-Ciernia A, et al. Among authors: kramar ea. Nat Neurosci. 2013 May;16(5):552-61. doi: 10.1038/nn.3359. Epub 2013 Mar 24. Nat Neurosci. 2013. PMID: 23525042 Free PMC article.
Mutation of neuron-specific chromatin remodeling subunit BAF53b: rescue of plasticity and memory by manipulating actin remodeling.
Vogel Ciernia A, Kramár EA, Matheos DP, Havekes R, Hemstedt TJ, Magnan CN, Sakata K, Tran A, Azzawi S, Lopez A, Dang R, Wang W, Trieu B, Tong J, Barrett RM, Post RJ, Baldi P, Abel T, Lynch G, Wood MA. Vogel Ciernia A, et al. Among authors: kramar ea. Learn Mem. 2017 Apr 17;24(5):199-209. doi: 10.1101/lm.044602.116. Print 2017 May. Learn Mem. 2017. PMID: 28416631 Free PMC article.
Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory.
Kwapis JL, Alaghband Y, Kramár EA, López AJ, Vogel Ciernia A, White AO, Shu G, Rhee D, Michael CM, Montellier E, Liu Y, Magnan CN, Chen S, Sassone-Corsi P, Baldi P, Matheos DP, Wood MA. Kwapis JL, et al. Among authors: kramar ea. Nat Commun. 2018 Aug 20;9(1):3323. doi: 10.1038/s41467-018-05868-0. Nat Commun. 2018. PMID: 30127461 Free PMC article.
70 results