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A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity.
Cornett EM, Dickson BM, Krajewski K, Spellmon N, Umstead A, Vaughan RM, Shaw KM, Versluis PP, Cowles MW, Brunzelle J, Yang Z, Vega IE, Sun ZW, Rothbart SB. Cornett EM, et al. Among authors: krajewski k. Sci Adv. 2018 Nov 28;4(11):eaav2623. doi: 10.1126/sciadv.aav2623. eCollection 2018 Nov. Sci Adv. 2018. PMID: 30498785 Free PMC article.
Peptide microarrays to interrogate the "histone code".
Rothbart SB, Krajewski K, Strahl BD, Fuchs SM. Rothbart SB, et al. Among authors: krajewski k. Methods Enzymol. 2012;512:107-35. doi: 10.1016/B978-0-12-391940-3.00006-8. Methods Enzymol. 2012. PMID: 22910205 Free PMC article.
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation.
Rothbart SB, Krajewski K, Nady N, Tempel W, Xue S, Badeaux AI, Barsyte-Lovejoy D, Martinez JY, Bedford MT, Fuchs SM, Arrowsmith CH, Strahl BD. Rothbart SB, et al. Among authors: krajewski k. Nat Struct Mol Biol. 2012 Nov;19(11):1155-60. doi: 10.1038/nsmb.2391. Epub 2012 Sep 30. Nat Struct Mol Biol. 2012. PMID: 23022729 Free PMC article.
An Interactive Database for the Assessment of Histone Antibody Specificity.
Rothbart SB, Dickson BM, Raab JR, Grzybowski AT, Krajewski K, Guo AH, Shanle EK, Josefowicz SZ, Fuchs SM, Allis CD, Magnuson TR, Ruthenburg AJ, Strahl BD. Rothbart SB, et al. Among authors: krajewski k. Mol Cell. 2015 Aug 6;59(3):502-11. doi: 10.1016/j.molcel.2015.06.022. Epub 2015 Jul 23. Mol Cell. 2015. PMID: 26212453 Free PMC article.
Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1.
Harrison JS, Cornett EM, Goldfarb D, DaRosa PA, Li ZM, Yan F, Dickson BM, Guo AH, Cantu DV, Kaustov L, Brown PJ, Arrowsmith CH, Erie DA, Major MB, Klevit RE, Krajewski K, Kuhlman B, Strahl BD, Rothbart SB. Harrison JS, et al. Among authors: krajewski k. Elife. 2016 Sep 6;5:e17101. doi: 10.7554/eLife.17101. Elife. 2016. PMID: 27595565 Free PMC article.
Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.
Zhang Y, Jang Y, Lee JE, Ahn J, Xu L, Holden MR, Cornett EM, Krajewski K, Klein BJ, Wang SP, Dou Y, Roeder RG, Strahl BD, Rothbart SB, Shi X, Ge K, Kutateladze TG. Zhang Y, et al. Among authors: krajewski k. Nat Commun. 2019 May 24;10(1):2314. doi: 10.1038/s41467-019-10324-8. Nat Commun. 2019. PMID: 31127101 Free PMC article.
324 results