Krainer G - Search Results

1

The Hsc70 disaggregation machinery removes monomer units directly from α-synuclein fibril ends.

Schneider MM, Gautam S, Herling TW, Andrzejewska E, Krainer G, Miller AM, Trinkaus VA, Peter QAE, Ruggeri FS, Vendruscolo M, Bracher A, Dobson CM, Hartl FU, Knowles TPJ. Schneider MM, et al. Among authors: krainer g. Nat Commun. 2021 Oct 14;12(1):5999. doi: 10.1038/s41467-021-25966-w. Nat Commun. 2021. PMID: 34650037 Free PMC article.

2

Microfluidic approaches for the analysis of protein-protein interactions in solution.

Arter WE, Levin A, Krainer G, Knowles TPJ. Arter WE, et al. Among authors: krainer g. Biophys Rev. 2020 Apr;12(2):575-585. doi: 10.1007/s12551-020-00679-4. Epub 2020 Apr 8. Biophys Rev. 2020. PMID: 32266673 Free PMC article. Review.

3

Rapid Structural, Kinetic, and Immunochemical Analysis of Alpha-Synuclein Oligomers in Solution.

Arter WE, Xu CK, Castellana-Cruz M, Herling TW, Krainer G, Saar KL, Kumita JR, Dobson CM, Knowles TPJ. Arter WE, et al. Among authors: krainer g. Nano Lett. 2020 Nov 11;20(11):8163-8169. doi: 10.1021/acs.nanolett.0c03260. Epub 2020 Oct 20. Nano Lett. 2020. PMID: 33079553 Free PMC article.

4

Interactions of α-synuclein oligomers with lipid membranes.

Musteikytė G, Jayaram AK, Xu CK, Vendruscolo M, Krainer G, Knowles TPJ. Musteikytė G, et al. Among authors: krainer g. Biochim Biophys Acta Biomembr. 2021 Apr 1;1863(4):183536. doi: 10.1016/j.bbamem.2020.183536. Epub 2020 Dec 26. Biochim Biophys Acta Biomembr. 2021. PMID: 33373595 Free article. Review.

5

Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions.

Krainer G, Welsh TJ, Joseph JA, Espinosa JR, Wittmann S, de Csilléry E, Sridhar A, Toprakcioglu Z, Gudiškytė G, Czekalska MA, Arter WE, Guillén-Boixet J, Franzmann TM, Qamar S, George-Hyslop PS, Hyman AA, Collepardo-Guevara R, Alberti S, Knowles TPJ. Krainer G, et al. Nat Commun. 2021 Feb 17;12(1):1085. doi: 10.1038/s41467-021-21181-9. Nat Commun. 2021. PMID: 33597515 Free PMC article.

6

Learning the molecular grammar of protein condensates from sequence determinants and embeddings.

Saar KL, Morgunov AS, Qi R, Arter WE, Krainer G, Lee AA, Knowles TPJ. Saar KL, et al. Among authors: krainer g. Proc Natl Acad Sci U S A. 2021 Apr 13;118(15):e2019053118. doi: 10.1073/pnas.2019053118. Proc Natl Acad Sci U S A. 2021. PMID: 33827920 Free PMC article.

7

Liquid-Liquid Phase-Separated Systems from Reversible Gel-Sol Transition of Protein Microgels.

Xu Y, Qi R, Zhu H, Li B, Shen Y, Krainer G, Klenerman D, Knowles TPJ. Xu Y, et al. Among authors: krainer g. Adv Mater. 2021 Aug;33(33):e2008670. doi: 10.1002/adma.202008670. Epub 2021 Jul 8. Adv Mater. 2021. PMID: 34235786

8

Conformational Expansion of Tau in Condensates Promotes Irreversible Aggregation.

Wen J, Hong L, Krainer G, Yao QQ, Knowles TPJ, Wu S, Perrett S. Wen J, et al. Among authors: krainer g. J Am Chem Soc. 2021 Aug 25;143(33):13056-13064. doi: 10.1021/jacs.1c03078. Epub 2021 Aug 10. J Am Chem Soc. 2021. PMID: 34374536 Free article.

9

Liquid-liquid phase separation underpins the formation of replication factories in rotaviruses.

Geiger F, Acker J, Papa G, Wang X, Arter WE, Saar KL, Erkamp NA, Qi R, Bravo JP, Strauss S, Krainer G, Burrone OR, Jungmann R, Knowles TP, Engelke H, Borodavka A. Geiger F, et al. Among authors: krainer g. EMBO J. 2021 Nov 2;40(21):e107711. doi: 10.15252/embj.2021107711. Epub 2021 Sep 15. EMBO J. 2021. PMID: 34524703 Free PMC article.

10

Surface Electrostatics Govern the Emulsion Stability of Biomolecular Condensates.

Welsh TJ, Krainer G, Espinosa JR, Joseph JA, Sridhar A, Jahnel M, Arter WE, Saar KL, Alberti S, Collepardo-Guevara R, Knowles TPJ. Welsh TJ, et al. Among authors: krainer g. Nano Lett. 2022 Jan 26;22(2):612-621. doi: 10.1021/acs.nanolett.1c03138. Epub 2022 Jan 10. Nano Lett. 2022. PMID: 35001622

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