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Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors.
Brem J, Panduwawala T, Hansen JU, Hewitt J, Liepins E, Donets P, Espina L, Farley AJM, Shubin K, Campillos GG, Kiuru P, Shishodia S, Krahn D, Leśniak RK, Schmidt Adrian J, Calvopiña K, Turrientes MC, Kavanagh ME, Lubriks D, Hinchliffe P, Langley GW, Aboklaish AF, Eneroth A, Backlund M, Baran AG, Nielsen EI, Speake M, Kuka J, Robinson J, Grinberga S, Robinson L, McDonough MA, Rydzik AM, Leissing TM, Jimenez-Castellanos JC, Avison MB, Da Silva Pinto S, Pannifer AD, Martjuga M, Widlake E, Priede M, Hopkins Navratilova I, Gniadkowski M, Belfrage AK, Brandt P, Yli-Kauhaluoma J, Bacque E, Page MGP, Björkling F, Tyrrell JM, Spencer J, Lang PA, Baranczewski P, Cantón R, McElroy SP, Jones PS, Baquero F, Suna E, Morrison A, Walsh TR, Schofield CJ. Brem J, et al. Among authors: krahn d. Nat Chem. 2022 Jan;14(1):15-24. doi: 10.1038/s41557-021-00831-x. Epub 2021 Dec 13. Nat Chem. 2022. PMID: 34903857
Proteasome activity imaging and profiling characterizes bacterial effector syringolin A.
Kolodziejek I, Misas-Villamil JC, Kaschani F, Clerc J, Gu C, Krahn D, Niessen S, Verdoes M, Willems LI, Overkleeft HS, Kaiser M, van der Hoorn RA. Kolodziejek I, et al. Among authors: krahn d. Plant Physiol. 2011 Jan;155(1):477-89. doi: 10.1104/pp.110.163733. Epub 2010 Nov 2. Plant Physiol. 2011. PMID: 21045122 Free PMC article.
Triazine Probes Target Ascorbate Peroxidases in Plants.
Morimoto K, Cole KS, Kourelis J, Witt CH, Brown D, Krahn D, Stegmann M, Kaschani F, Kaiser M, Burton J, Mohammed S, Yamaguchi-Shinozaki K, Weerapana E, van der Hoorn RAL. Morimoto K, et al. Among authors: krahn d. Plant Physiol. 2019 Aug;180(4):1848-1859. doi: 10.1104/pp.19.00481. Epub 2019 May 28. Plant Physiol. 2019. PMID: 31138623 Free PMC article.
Extracellular proteolytic cascade in tomato activates immune protease Rcr3.
Paulus JK, Kourelis J, Ramasubramanian S, Homma F, Godson A, Hörger AC, Hong TN, Krahn D, Ossorio Carballo L, Wang S, Win J, Smoker M, Kamoun S, Dong S, van der Hoorn RAL. Paulus JK, et al. Among authors: krahn d. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17409-17417. doi: 10.1073/pnas.1921101117. Epub 2020 Jul 2. Proc Natl Acad Sci U S A. 2020. PMID: 32616567 Free PMC article.
The chemical compound 'Heatin' stimulates hypocotyl elongation and interferes with the Arabidopsis NIT1-subfamily of nitrilases.
van der Woude L, Piotrowski M, Klaasse G, Paulus JK, Krahn D, Ninck S, Kaschani F, Kaiser M, Novák O, Ljung K, Bulder S, van Verk M, Snoek BL, Fiers M, Martin NI, van der Hoorn RAL, Robert S, Smeekens S, van Zanten M. van der Woude L, et al. Among authors: krahn d. Plant J. 2021 Jun;106(6):1523-1540. doi: 10.1111/tpj.15250. Epub 2021 May 6. Plant J. 2021. PMID: 33768644 Free PMC article.
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[No authors listed] [No authors listed] PMID: 33885892
135 results