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Page 1
Preclinical development of a miR-132 inhibitor for heart failure treatment.
Foinquinos A, Batkai S, Genschel C, Viereck J, Rump S, Gyöngyösi M, Traxler D, Riesenhuber M, Spannbauer A, Lukovic D, Weber N, Zlabinger K, Hašimbegović E, Winkler J, Fiedler J, Dangwal S, Fischer M, de la Roche J, Wojciechowski D, Kraft T, Garamvölgyi R, Neitzel S, Chatterjee S, Yin X, Bär C, Mayr M, Xiao K, Thum T. Foinquinos A, et al. Among authors: kraft t. Nat Commun. 2020 Jan 31;11(1):633. doi: 10.1038/s41467-020-14349-2. Nat Commun. 2020. PMID: 32005803 Free PMC article.
Stiff matrix induces switch to pure β-cardiac myosin heavy chain expression in human ESC-derived cardiomyocytes.
Weber N, Schwanke K, Greten S, Wendland M, Iorga B, Fischer M, Geers-Knörr C, Hegermann J, Wrede C, Fiedler J, Kempf H, Franke A, Piep B, Pfanne A, Thum T, Martin U, Brenner B, Zweigerdt R, Kraft T. Weber N, et al. Among authors: kraft t. Basic Res Cardiol. 2016 Nov;111(6):68. doi: 10.1007/s00395-016-0587-9. Epub 2016 Oct 14. Basic Res Cardiol. 2016. PMID: 27743117
Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture.
Halloin C, Schwanke K, Löbel W, Franke A, Szepes M, Biswanath S, Wunderlich S, Merkert S, Weber N, Osten F, de la Roche J, Polten F, Christoph Wollert K, Kraft T, Fischer M, Martin U, Gruh I, Kempf H, Zweigerdt R. Halloin C, et al. Among authors: kraft t. Stem Cell Reports. 2019 Aug 13;13(2):366-379. doi: 10.1016/j.stemcr.2019.06.004. Epub 2019 Jul 25. Stem Cell Reports. 2019. PMID: 31353227 Free PMC article.
TIP30 counteracts cardiac hypertrophy and failure by inhibiting translational elongation.
Grund A, Szaroszyk M, Korf-Klingebiel M, Malek Mohammadi M, Trogisch FA, Schrameck U, Gigina A, Tiedje C, Gaestel M, Kraft T, Hegermann J, Batkai S, Thum T, Perrot A, Remedios CD, Riechert E, Völkers M, Doroudgar S, Jungmann A, Bauer R, Yin X, Mayr M, Wollert KC, Pich A, Xiao H, Katus HA, Bauersachs J, Müller OJ, Heineke J. Grund A, et al. Among authors: kraft t. EMBO Mol Med. 2019 Oct;11(10):e10018. doi: 10.15252/emmm.201810018. Epub 2019 Aug 30. EMBO Mol Med. 2019. PMID: 31468715 Free PMC article.
Advanced Single-Cell Mapping Reveals that in hESC Cardiomyocytes Contraction Kinetics and Action Potential Are Independent of Myosin Isoform.
Weber N, Kowalski K, Holler T, Radocaj A, Fischer M, Thiemann S, de la Roche J, Schwanke K, Piep B, Peschel N, Krumm U, Lingk A, Wendland M, Greten S, Schmitto JD, Ismail I, Warnecke G, Zywietz U, Chichkov B, Meißner J, Haverich A, Martin U, Brenner B, Zweigerdt R, Kraft T. Weber N, et al. Among authors: kraft t. Stem Cell Reports. 2020 May 12;14(5):788-802. doi: 10.1016/j.stemcr.2020.03.015. Epub 2020 Apr 16. Stem Cell Reports. 2020. PMID: 32302556 Free PMC article.
Targeting muscle-enriched long non-coding RNA H19 reverses pathological cardiac hypertrophy.
Viereck J, Bührke A, Foinquinos A, Chatterjee S, Kleeberger JA, Xiao K, Janssen-Peters H, Batkai S, Ramanujam D, Kraft T, Cebotari S, Gueler F, Beyer AM, Schmitz J, Bräsen JH, Schmitto JD, Gyöngyösi M, Löser A, Hirt MN, Eschenhagen T, Engelhardt S, Bär C, Thum T. Viereck J, et al. Among authors: kraft t. Eur Heart J. 2020 Sep 21;41(36):3462-3474. doi: 10.1093/eurheartj/ehaa519. Eur Heart J. 2020. PMID: 32657324 Free PMC article.
Myeloid-Derived Growth Factor Protects Against Pressure Overload-Induced Heart Failure by Preserving Sarco/Endoplasmic Reticulum Ca2+-ATPase Expression in Cardiomyocytes.
Korf-Klingebiel M, Reboll MR, Polten F, Weber N, Jäckle F, Wu X, Kallikourdis M, Kunderfranco P, Condorelli G, Giannitsis E, Kustikova OS, Schambach A, Pich A, Widder JD, Bauersachs J, van den Heuvel J, Kraft T, Wang Y, Wollert KC. Korf-Klingebiel M, et al. Among authors: kraft t. Circulation. 2021 Oct 12;144(15):1227-1240. doi: 10.1161/CIRCULATIONAHA.120.053365. Epub 2021 Aug 10. Circulation. 2021. PMID: 34372689
311 results