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MSUT2 is a determinant of susceptibility to tau neurotoxicity.
Guthrie CR, Greenup L, Leverenz JB, Kraemer BC. Guthrie CR, et al. Among authors: kraemer bc. Hum Mol Genet. 2011 May 15;20(10):1989-99. doi: 10.1093/hmg/ddr079. Epub 2011 Feb 25. Hum Mol Genet. 2011. PMID: 21355046 Free PMC article.
Potential neuroprotective strategies against tauopathy.
Wheeler JM, Guthrie CR, Kraemer BC. Wheeler JM, et al. Among authors: kraemer bc. Biochem Soc Trans. 2012 Aug;40(4):656-60. doi: 10.1042/BST20120017. Biochem Soc Trans. 2012. PMID: 22817711 Free PMC article.
Epigenetic signature and enhancer activity of the human APOE gene.
Yu CE, Cudaback E, Foraker J, Thomson Z, Leong L, Lutz F, Gill JA, Saxton A, Kraemer B, Navas P, Keene CD, Montine T, Bekris LM. Yu CE, et al. Hum Mol Genet. 2013 Dec 15;22(24):5036-47. doi: 10.1093/hmg/ddt354. Epub 2013 Jul 25. Hum Mol Genet. 2013. PMID: 23892237 Free PMC article.
The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43.
Liachko NF, McMillan PJ, Strovas TJ, Loomis E, Greenup L, Murrell JR, Ghetti B, Raskind MA, Montine TJ, Bird TD, Leverenz JB, Kraemer BC. Liachko NF, et al. Among authors: kraemer bc. PLoS Genet. 2014 Dec 4;10(12):e1004803. doi: 10.1371/journal.pgen.1004803. eCollection 2014 Dec. PLoS Genet. 2014. PMID: 25473830 Free PMC article.
High copy wildtype human 1N4R tau expression promotes early pathological tauopathy accompanied by cognitive deficits without progressive neurofibrillary degeneration.
Wheeler JM, McMillan PJ, Hawk M, Iba M, Robinson L, Xu GJ, Dombroski BA, Jeong D, Dichter MA, Juul H, Loomis E, Raskind M, Leverenz JB, Trojanowski JQ, Lee VM, Schellenberg GD, Kraemer BC. Wheeler JM, et al. Among authors: kraemer bc. Acta Neuropathol Commun. 2015 Jun 4;3:33. doi: 10.1186/s40478-015-0210-6. Acta Neuropathol Commun. 2015. PMID: 26041339 Free PMC article.
The phosphatase calcineurin regulates pathological TDP-43 phosphorylation.
Liachko NF, Saxton AD, McMillan PJ, Strovas TJ, Currey HN, Taylor LM, Wheeler JM, Oblak AL, Ghetti B, Montine TJ, Keene CD, Raskind MA, Bird TD, Kraemer BC. Liachko NF, et al. Among authors: kraemer bc. Acta Neuropathol. 2016 Oct;132(4):545-61. doi: 10.1007/s00401-016-1600-y. Epub 2016 Jul 29. Acta Neuropathol. 2016. PMID: 27473149 Free PMC article.
75 results