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Presence of immunogenic alternatively spliced insulin gene product in human pancreatic delta cells.
Diabetologia. 2023 May;66(5):884-896. doi: 10.1007/s00125-023-05882-y. Epub 2023 Mar 8.
Diabetologia. 2023.
PMID: 36884057
Free PMC article.
Neoantigens and Microenvironment in Type 1 Diabetes: Lessons from Antitumor Immunity.
Kracht MJL, Zaldumbide A, Roep BO.
Kracht MJL, et al.
Trends Endocrinol Metab. 2016 Jun;27(6):353-362. doi: 10.1016/j.tem.2016.03.013. Epub 2016 Apr 16.
Trends Endocrinol Metab. 2016.
PMID: 27094501
Review.
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Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes.
Kracht MJ, van Lummel M, Nikolic T, Joosten AM, Laban S, van der Slik AR, van Veelen PA, Carlotti F, de Koning EJ, Hoeben RC, Zaldumbide A, Roep BO.
Kracht MJ, et al.
Nat Med. 2017 Apr;23(4):501-507. doi: 10.1038/nm.4289. Epub 2017 Feb 27.
Nat Med. 2017.
PMID: 28263308
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Bioluminescent reporter assay for monitoring ER stress in human beta cells.
Kracht MJL, de Koning EJP, Hoeben RC, Roep BO, Zaldumbide A.
Kracht MJL, et al.
Sci Rep. 2018 Dec 10;8(1):17738. doi: 10.1038/s41598-018-36142-4.
Sci Rep. 2018.
PMID: 30532033
Free PMC article.
Item in Clipboard
β-Cell Stress Shapes CTL Immune Recognition of Preproinsulin Signal Peptide by Posttranscriptional Regulation of Endoplasmic Reticulum Aminopeptidase 1.
Thomaidou S, Kracht MJL, van der Slik A, Laban S, de Koning EJ, Carlotti F, Hoeben RC, Roep BO, Zaldumbide A.
Thomaidou S, et al. Among authors: kracht mjl.
Diabetes. 2020 Apr;69(4):670-680. doi: 10.2337/db19-0984. Epub 2020 Jan 2.
Diabetes. 2020.
PMID: 31896552
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A roadmap of the generation of neoantigens as targets of the immune system in type 1 diabetes.
Roep BO, Kracht MJ, van Lummel M, Zaldumbide A.
Roep BO, et al.
Curr Opin Immunol. 2016 Dec;43:67-73. doi: 10.1016/j.coi.2016.09.007. Epub 2016 Oct 7.
Curr Opin Immunol. 2016.
PMID: 27723537
Free article.
Review.
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Targeting citrullination in autoimmunity: insights learned from preclinical mouse models.
Bruggeman Y, Sodré FMC, Buitinga M, Mathieu C, Overbergh L, Kracht MJL.
Bruggeman Y, et al. Among authors: kracht mjl.
Expert Opin Ther Targets. 2021 Apr;25(4):269-281. doi: 10.1080/14728222.2021.1918104. Epub 2021 May 4.
Expert Opin Ther Targets. 2021.
PMID: 33896351
Review.
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