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Specific Inhibitors of HIV Capsid Assembly Binding to the C-Terminal Domain of the Capsid Protein: Evaluation of 2-Arylquinazolines as Potential Antiviral Compounds.
Machara A, Lux V, Kožíšek M, Grantz Šašková K, Štěpánek O, Kotora M, Parkan K, Pávová M, Glass B, Sehr P, Lewis J, Müller B, Kräusslich HG, Konvalinka J. Machara A, et al. J Med Chem. 2016 Jan 28;59(2):545-58. doi: 10.1021/acs.jmedchem.5b01089. Epub 2016 Jan 6. J Med Chem. 2016. PMID: 26685880
Design of HIV protease inhibitors based on inorganic polyhedral metallacarboranes.
Rezácová P, Pokorná J, Brynda J, Kozísek M, Cígler P, Lepsík M, Fanfrlík J, Rezác J, Grantz Sasková K, Sieglová I, Plesek J, Sícha V, Grüner B, Oberwinkler H, Sedlácek' J, Kräusslich HG, Hobza P, Král V, Konvalinka J. Rezácová P, et al. J Med Chem. 2009 Nov 26;52(22):7132-41. doi: 10.1021/jm9011388. J Med Chem. 2009. PMID: 19874035
From nonpeptide toward noncarbon protease inhibitors: metallacarboranes as specific and potent inhibitors of HIV protease.
Cígler P, Kozísek M, Rezácová P, Brynda J, Otwinowski Z, Pokorná J, Plesek J, Grüner B, Dolecková-Maresová L, Mása M, Sedlácek J, Bodem J, Kräusslich HG, Král V, Konvalinka J. Cígler P, et al. Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15394-9. doi: 10.1073/pnas.0507577102. Epub 2005 Oct 14. Proc Natl Acad Sci U S A. 2005. PMID: 16227435 Free PMC article.
Retroviral proteases and their roles in virion maturation.
Konvalinka J, Kräusslich HG, Müller B. Konvalinka J, et al. Virology. 2015 May;479-480:403-17. doi: 10.1016/j.virol.2015.03.021. Epub 2015 Mar 26. Virology. 2015. PMID: 25816761 Free article. Review.
Configurations of diastereomeric hydroxyethylene isosteres strongly affect biological activities of a series of specific inhibitors of human-immunodeficiency-virus proteinase.
Konvalinka J, Litera J, Weber J, Vondrásek J, Hradílek M, Soucek M, Pichová I, Majer P, Strop P, Sedlácek J, Heuser AM, Kottler H, Kräusslich HG. Konvalinka J, et al. Eur J Biochem. 1997 Dec 1;250(2):559-66. doi: 10.1111/j.1432-1033.1997.0559a.x. Eur J Biochem. 1997. PMID: 9428710 Free article.
A modular approach to HIV-1 proteinase inhibitor design.
Uhlíková T, Konvalinka J, Pichová I, Soucek M, Kräusslich HG, Vondrásek J. Uhlíková T, et al. Biochem Biophys Res Commun. 1996 May 6;222(1):38-43. doi: 10.1006/bbrc.1996.0694. Biochem Biophys Res Commun. 1996. PMID: 8630071
279 results