Krüger R - Search Results

1

Low-bias phosphopeptide enrichment from scarce samples using plastic antibodies.

Chen J, Shinde S, Koch MH, Eisenacher M, Galozzi S, Lerari T, Barkovits K, Subedi P, Krüger R, Kuhlmann K, Sellergren B, Helling S, Marcus K. Chen J, et al. Among authors: kruger r. Sci Rep. 2015 Jul 1;5:11438. doi: 10.1038/srep11438. Sci Rep. 2015. PMID: 26126808 Free PMC article.

2

Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2.

Casadei N, Sood P, Ulrich T, Fallier-Becker P, Kieper N, Helling S, May C, Glaab E, Chen J, Nuber S, Wolburg H, Marcus K, Rapaport D, Ott T, Riess O, Krüger R, Fitzgerald JC. Casadei N, et al. Among authors: kruger r. Hum Mol Genet. 2016 Feb 1;25(3):459-71. doi: 10.1093/hmg/ddv485. Epub 2015 Nov 24. Hum Mol Genet. 2016. PMID: 26604148

3

Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2.

Casadei N, Sood P, Ulrich T, Fallier-Becker P, Kieper N, Helling S, May C, Glaab E, Chen J, Nuber S, Wolburg H, Marcus K, Rapaport D, Ott T, Riess O, Krüger R, Fitzgerald JC. Casadei N, et al. Among authors: kruger r. Hum Mol Genet. 2016 Dec 15;25(24):5513. doi: 10.1093/hmg/ddw353. Hum Mol Genet. 2016. PMID: 28031291 No abstract available.

4

The GBAP1 pseudogene acts as a ceRNA for the glucocerebrosidase gene GBA by sponging miR-22-3p.

Straniero L, Rimoldi V, Samarani M, Goldwurm S, Di Fonzo A, Krüger R, Deleidi M, Aureli M, Soldà G, Duga S, Asselta R. Straniero L, et al. Among authors: kruger r. Sci Rep. 2017 Oct 5;7(1):12702. doi: 10.1038/s41598-017-12973-5. Sci Rep. 2017. PMID: 28983119 Free PMC article.

5

A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease.

Boussaad I, Obermaier CD, Hanss Z, Bobbili DR, Bolognin S, Glaab E, Wołyńska K, Weisschuh N, De Conti L, May C, Giesert F, Grossmann D, Lambert A, Kirchen S, Biryukov M, Burbulla LF, Massart F, Bohler J, Cruciani G, Schmid B, Kurz-Drexler A, May P, Duga S, Klein C, Schwamborn JC, Marcus K, Woitalla D, Vogt Weisenhorn DM, Wurst W, Baralle M, Krainc D, Gasser T, Wissinger B, Krüger R. Boussaad I, et al. Among authors: kruger r. Sci Transl Med. 2020 Sep 9;12(560):eaau3960. doi: 10.1126/scitranslmed.aau3960. Sci Transl Med. 2020. PMID: 32908004

6

Haploinsufficiency due to a novel ACO2 deletion causes mitochondrial dysfunction in fibroblasts from a patient with dominant optic nerve atrophy.

Neumann MA, Grossmann D, Schimpf-Linzenbold S, Dayan D, Stingl K, Ben-Menachem R, Pines O, Massart F, Delcambre S, Ghelfi J, Bohler J, Strom T, Kessel A, Azem A, Schöls L, Grünewald A, Wissinger B, Krüger R. Neumann MA, et al. Among authors: kruger r. Sci Rep. 2020 Oct 7;10(1):16736. doi: 10.1038/s41598-020-73557-4. Sci Rep. 2020. PMID: 33028849 Free PMC article.

7

Integrated, automated maintenance, expansion and differentiation of 2D and 3D patient-derived cellular models for high throughput drug screening.

Boussaad I, Cruciani G, Bolognin S, Antony P, Dording CM, Kwon YJ, Heutink P, Fava E, Schwamborn JC, Krüger R. Boussaad I, et al. Among authors: kruger r. Sci Rep. 2021 Jan 14;11(1):1439. doi: 10.1038/s41598-021-81129-3. Sci Rep. 2021. PMID: 33446877 Free PMC article.

8

PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons.

Brown SJ, Boussaad I, Jarazo J, Fitzgerald JC, Antony P, Keatinge M, Blechman J, Schwamborn JC, Krüger R, Placzek M, Bandmann O. Brown SJ, et al. Among authors: kruger r. Sci Rep. 2021 Mar 23;11(1):6617. doi: 10.1038/s41598-021-84278-7. Sci Rep. 2021. PMID: 33758225 Free PMC article.

9

Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function.

Barbuti PA, Ohnmacht J, Santos BFR, Antony PM, Massart F, Cruciani G, Dording CM, Pavelka L, Casadei N, Kwon YJ, Krüger R. Barbuti PA, et al. Among authors: kruger r. Sci Rep. 2021 Nov 9;11(1):21946. doi: 10.1038/s41598-021-01505-x. Sci Rep. 2021. PMID: 34754035 Free PMC article.

10

Age at onset as stratifier in idiopathic Parkinson's disease - effect of ageing and polygenic risk score on clinical phenotypes.

Pavelka L, Rauschenberger A, Landoulsi Z, Pachchek S, May P, Glaab E, Krüger R; NCER-PD Consortium. Pavelka L, et al. Among authors: kruger r. NPJ Parkinsons Dis. 2022 Aug 9;8(1):102. doi: 10.1038/s41531-022-00342-7. NPJ Parkinsons Dis. 2022. PMID: 35945230 Free PMC article.

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