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Therapeutic Application of Alpha-1 Antitrypsin in COVID-19.
Ritzmann F, Chitirala P, Krüger N, Hoffmann M, Zuo W, Lammert F, Smola S, Tov N, Alagem N, Lepper PM, Pöhlmann S, Beisswenger C, Herr C, Bals R; AAT-in-COVID-19 Study Group. Ritzmann F, et al. Among authors: kruger n. Am J Respir Crit Care Med. 2021 Jul 15;204(2):224-227. doi: 10.1164/rccm.202104-0833LE. Am J Respir Crit Care Med. 2021. PMID: 33961754 Free PMC article. No abstract available.
Tetherin Inhibits Nipah Virus but Not Ebola Virus Replication in Fruit Bat Cells.
Hoffmann M, Nehlmeier I, Brinkmann C, Krähling V, Behner L, Moldenhauer AS, Krüger N, Nehls J, Schindler M, Hoenen T, Maisner A, Becker S, Pöhlmann S. Hoffmann M, et al. Among authors: kruger n. J Virol. 2019 Jan 17;93(3):e01821-18. doi: 10.1128/JVI.01821-18. Print 2019 Feb 1. J Virol. 2019. PMID: 30429347 Free PMC article.
Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of endosomal cathepsins.
Plegge T, Spiegel M, Krüger N, Nehlmeier I, Winkler M, González Hernández M, Pöhlmann S. Plegge T, et al. Among authors: kruger n. PLoS One. 2019 Apr 11;14(4):e0214968. doi: 10.1371/journal.pone.0214968. eCollection 2019. PLoS One. 2019. PMID: 30973897 Free PMC article.
Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2.
Hoffmann M, Mösbauer K, Hofmann-Winkler H, Kaul A, Kleine-Weber H, Krüger N, Gassen NC, Müller MA, Drosten C, Pöhlmann S. Hoffmann M, et al. Among authors: kruger n. Nature. 2020 Sep;585(7826):588-590. doi: 10.1038/s41586-020-2575-3. Epub 2020 Jul 22. Nature. 2020. PMID: 32698190
Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity.
Hoffmann M, Hofmann-Winkler H, Smith JC, Krüger N, Sørensen LK, Søgaard OS, Hasselstrøm JB, Winkler M, Hempel T, Raich L, Olsson S, Yamazoe T, Yamatsuta K, Mizuno H, Ludwig S, Noé F, Sheltzer JM, Kjolby M, Pöhlmann S. Hoffmann M, et al. Among authors: kruger n. bioRxiv [Preprint]. 2020 Aug 5:2020.08.05.237651. doi: 10.1101/2020.08.05.237651. bioRxiv. 2020. PMID: 32793911 Free PMC article. Updated. Preprint.
250 results