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High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of Plasmodium falciparum.
Johannsen S, Gierse RM, Krüger A, Edwards RL, Nanna V, Fontana A, Zhu D, Masini T, de Carvalho LP, Poizat M, Kieftenbelt B, Hodge DM, Alvarez S, Bunt D, Lacour A, Shams A, Meissner KA, de Souza EE, Dröge M, van Vliet B, den Hartog J, Hutter MC, Held J, Odom John AR, Wrenger C, Hirsch AKH. Johannsen S, et al. Among authors: kruger a. ACS Infect Dis. 2024 Mar 8;10(3):1000-1022. doi: 10.1021/acsinfecdis.3c00670. Epub 2024 Feb 17. ACS Infect Dis. 2024. PMID: 38367280 Free PMC article.
Novel Highlight in Malarial Drug Discovery: Aspartate Transcarbamoylase.
Wang C, Krüger A, Du X, Wrenger C, Groves MR. Wang C, et al. Among authors: kruger a. Front Cell Infect Microbiol. 2022 Mar 4;12:841833. doi: 10.3389/fcimb.2022.841833. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35310840 Free PMC article. Review.
1,3-Diphenylureido hydroxamate as a promising scaffold for generation of potent antimalarial histone deacetylase inhibitors.
Tavares MT, Krüger A, Yan SLR, Waitman KB, Gomes VM, de Oliveira DS, Paz F, Hilscher S, Schutkowski M, Sippl W, Ruiz C, Toledo MFZJ, Hassimotto NMA, Machado-Neto JA, Poso A, Cameron MD, Bannister TD, Palmisano G, Wrenger C, Kronenberger T, Parise-Filho R. Tavares MT, et al. Among authors: kruger a. Sci Rep. 2023 Nov 29;13(1):21006. doi: 10.1038/s41598-023-47959-z. Sci Rep. 2023. PMID: 38030668 Free PMC article.
Aptamer Applications in Emerging Viral Diseases.
Krüger A, de Jesus Santos AP, de Sá V, Ulrich H, Wrenger C. Krüger A, et al. Pharmaceuticals (Basel). 2021 Jun 28;14(7):622. doi: 10.3390/ph14070622. Pharmaceuticals (Basel). 2021. PMID: 34203242 Free PMC article. Review.
1,111 results