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Abatacept inhibits inflammation and onset of rheumatoid arthritis in individuals at high risk (ARIAA): a randomised, international, multicentre, double-blind, placebo-controlled trial.
Rech J, Tascilar K, Hagen M, Kleyer A, Manger B, Schoenau V, Hueber AJ, Kleinert S, Baraliakos X, Braun J, Kiltz U, Fleck M, Rubbert-Roth A, Kofler DM, Behrens F, Feuchtenberger M, Zaenker M, Voll R, Venhoff N, Thiel J, Glaser C, Feist E, Burmester GR, Karberg K, Strunk J, Cañete JD, Senolt L, Filkova M, Naredo E, Largo R, Krönke G, D'Agostino MA, Østergaard M, Schett G. Rech J, et al. Among authors: kronke g. Lancet. 2024 Mar 2;403(10429):850-859. doi: 10.1016/S0140-6736(23)02650-8. Epub 2024 Feb 13. Lancet. 2024. PMID: 38364841 Clinical Trial.
Development of myeloproliferative disease in 12/15-lipoxygenase deficiency.
Taylor PR, Heydeck D, Jones GW, Krönke G, Funk CD, Knapper S, Adams D, Kühn H, O'Donnell VB. Taylor PR, et al. Among authors: kronke g. Blood. 2012 Jun 21;119(25):6173-4; author reply 6174-5. doi: 10.1182/blood-2012-02-410928. Blood. 2012. PMID: 22730527 Free PMC article. No abstract available.
Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature.
Kelkka T, Kienhöfer D, Hoffmann M, Linja M, Wing K, Sareila O, Hultqvist M, Laajala E, Chen Z, Vasconcelos J, Neves E, Guedes M, Marques L, Krönke G, Helminen M, Kainulainen L, Olofsson P, Jalkanen S, Lahesmaa R, Souto-Carneiro MM, Holmdahl R. Kelkka T, et al. Among authors: kronke g. Antioxid Redox Signal. 2014 Dec 1;21(16):2231-45. doi: 10.1089/ars.2013.5828. Epub 2014 Jul 29. Antioxid Redox Signal. 2014. PMID: 24787605 Free PMC article.
12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis.
Krönke G, Katzenbeisser J, Uderhardt S, Zaiss MM, Scholtysek C, Schabbauer G, Zarbock A, Koenders MI, Axmann R, Zwerina J, Baenckler HW, van den Berg W, Voll RE, Kühn H, Joosten LA, Schett G. Krönke G, et al. J Immunol. 2009 Sep 1;183(5):3383-9. doi: 10.4049/jimmunol.0900327. Epub 2009 Aug 12. J Immunol. 2009. PMID: 19675173 Free article.
137 results