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Attrition of X Chromosome Inactivation in Aged Hematopoietic Stem Cells.
Grigoryan A, Pospiech J, Krämer S, Lipka D, Liehr T, Geiger H, Kimura H, Mulaw MA, Florian MC. Grigoryan A, et al. Among authors: kramer s. Stem Cell Reports. 2021 Apr 13;16(4):708-716. doi: 10.1016/j.stemcr.2021.03.007. Epub 2021 Apr 1. Stem Cell Reports. 2021. PMID: 33798450 Free PMC article.
DNMT1 Deficiency Impacts on Plasmacytoid Dendritic Cells in Homeostasis and Autoimmune Disease.
Czeh M, Stäble S, Krämer S, Tepe L, Talyan S, Carrelha J, Meng Y, Heitplatz B, Schwabenland M, Milsom MD, Plass C, Prinz M, Schlesner M, Andrade-Navarro MA, Nerlov C, Jacobsen SEW, Lipka DB, Rosenbauer F. Czeh M, et al. Among authors: kramer s. J Immunol. 2022 Jan 15;208(2):358-370. doi: 10.4049/jimmunol.2100624. Epub 2021 Dec 13. J Immunol. 2022. PMID: 34903641 Free PMC article.
Hotspot DNMT3A mutations in clonal hematopoiesis and acute myeloid leukemia sensitize cells to azacytidine via viral mimicry response.
Scheller M, Ludwig AK, Göllner S, Rohde C, Krämer S, Stäble S, Janssen M, Müller JA, He L, Bäumer N, Arnold C, Gerß J, Schönung M, Thiede C, Niederwieser C, Niederwieser D, Serve H, Berdel WE, Thiem U, Hemmerling I, Leuschner F, Plass C, Schlesner M, Zaugg J, Milsom MD, Trumpp A, Pabst C, Lipka DB, Müller-Tidow C. Scheller M, et al. Among authors: kramer s. Nat Cancer. 2021 May;2(5):527-544. doi: 10.1038/s43018-021-00213-9. Epub 2021 May 25. Nat Cancer. 2021. PMID: 35122024
Dynamic DNA methylation reveals novel cis-regulatory elements in mouse hematopoiesis.
Schönung M, Hartmann M, Krämer S, Stäble S, Hakobyan M, Kleinert E, Aurich T, Cobanoglu D, Heidel FH, Fröhling S, Milsom MD, Schlesner M, Lutsik P, Lipka DB. Schönung M, et al. Among authors: kramer s. Exp Hematol. 2023 Jan;117:24-42.e7. doi: 10.1016/j.exphem.2022.11.001. Epub 2022 Nov 8. Exp Hematol. 2023. PMID: 36368558
Analysis of mutational signatures with yet another package for signature analysis.
Hübschmann D, Jopp-Saile L, Andresen C, Krämer S, Gu Z, Heilig CE, Kreutzfeldt S, Teleanu V, Fröhling S, Eils R, Schlesner M. Hübschmann D, et al. Among authors: kramer s. Genes Chromosomes Cancer. 2021 May;60(5):314-331. doi: 10.1002/gcc.22918. Epub 2020 Dec 31. Genes Chromosomes Cancer. 2021. PMID: 33222322
Defective homologous recombination DNA repair as therapeutic target in advanced chordoma.
Gröschel S, Hübschmann D, Raimondi F, Horak P, Warsow G, Fröhlich M, Klink B, Gieldon L, Hutter B, Kleinheinz K, Bonekamp D, Marschal O, Chudasama P, Mika J, Groth M, Uhrig S, Krämer S, Heining C, Heilig CE, Richter D, Reisinger E, Pfütze K, Eils R, Wolf S, von Kalle C, Brandts C, Scholl C, Weichert W, Richter S, Bauer S, Penzel R, Schröck E, Stenzinger A, Schlenk RF, Brors B, Russell RB, Glimm H, Schlesner M, Fröhling S. Gröschel S, et al. Among authors: kramer s. Nat Commun. 2019 Apr 9;10(1):1635. doi: 10.1038/s41467-019-09633-9. Nat Commun. 2019. PMID: 30967556 Free PMC article.
ShinyButchR: Interactive NMF-based decomposition workflow of genome-scale datasets.
Quintero A, Hübschmann D, Kurzawa N, Steinhauser S, Rentzsch P, Krämer S, Andresen C, Park J, Eils R, Schlesner M, Herrmann C. Quintero A, et al. Among authors: kramer s. Biol Methods Protoc. 2020 Oct 29;5(1):bpaa022. doi: 10.1093/biomethods/bpaa022. eCollection 2020. Biol Methods Protoc. 2020. PMID: 33376806 Free PMC article.
Backbone circularization of Bacillus subtilis family 11 xylanase increases its thermostability and its resistance against aggregation.
Waldhauer MC, Schmitz SN, Ahlmann-Eltze C, Gleixner JG, Schmelas CC, Huhn AG, Bunne C, Büscher M, Horn M, Klughammer N, Kreft J, Schäfer E, Bayer PA, Krämer SG, Neugebauer J, Wehler P, Mayer MP, Eils R, Di Ventura B. Waldhauer MC, et al. Mol Biosyst. 2015 Dec;11(12):3231-43. doi: 10.1039/c5mb00341e. Mol Biosyst. 2015. PMID: 26434634
2,018 results