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A subset of type-II collagen-binding antibodies prevents experimental arthritis by inhibiting FCGR3 signaling in neutrophils.
Xu Z, Xu B, Lundström SL, Moreno-Giró À, Zhao D, Martin M, Lönnblom E, Li Q, Krämer A, Ge C, Cheng L, Liang B, Tong D, Stawikowska R, Blom AM, Fields GB, Zubarev RA, Holmdahl R. Xu Z, et al. Among authors: kramer a. Nat Commun. 2023 Sep 23;14(1):5949. doi: 10.1038/s41467-023-41561-7. Nat Commun. 2023. PMID: 37741824 Free PMC article.
Pathogenic antibody response to glucose-6-phosphate isomerase targets a modified epitope uniquely exposed on joint cartilage.
Li T, Ge C, Krämer A, Sareila O, Leu Agelii M, Johansson L, Forslind K, Lönnblom E, Yang M, Xu B, Li Q, Cheng L, Bergström G, Fernandez G, Kastbom A, Rantapää-Dahlqvist S, Gjertsson I, Holmdahl R. Li T, et al. Among authors: kramer a. Ann Rheum Dis. 2023 Jun;82(6):799-808. doi: 10.1136/ard-2022-223633. Epub 2023 Mar 1. Ann Rheum Dis. 2023. PMID: 36858822
Antigen-presenting autoreactive B cells activate regulatory T cells and suppress autoimmune arthritis in mice.
Aoun M, Coelho A, Krämer A, Saxena A, Sabatier P, Beusch CM, Lönnblom E, Geng M, Do NN, Xu Z, Zhang J, He Y, Romero Castillo L, Abolhassani H, Xu B, Viljanen J, Rorbach J, Fernandez Lahore G, Gjertsson I, Kastbom A, Sjöwall C, Kihlberg J, Zubarev RA, Burkhardt H, Holmdahl R. Aoun M, et al. Among authors: kramer a. J Exp Med. 2023 Nov 6;220(11):e20230101. doi: 10.1084/jem.20230101. Epub 2023 Sep 11. J Exp Med. 2023. PMID: 37695523 Free PMC article.
Correction: Antigen-presenting autoreactive B cells activate regulatory T cells and suppress autoimmune arthritis in mice.
Aoun M, Coelho A, Krämer A, Saxena A, Sabatier P, Beusch CM, Lönnblom E, Geng M, Do NN, Xu Z, Zhang J, He Y, Castillo LR, Abolhassani H, Xu B, Viljanen J, Rorbach J, Lahore GF, Gjertsson I, Kastbom A, Sjöwall C, Kihlberg J, Zubarev RA, Burkhardt H, Holmdahl R. Aoun M, et al. Among authors: kramer a. J Exp Med. 2023 Nov 6;220(11):e2023010109212023c. doi: 10.1084/jem.2023010109212023c. Epub 2023 Oct 3. J Exp Med. 2023. PMID: 37788218 Free PMC article. No abstract available.
2,979 results