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Molecular design, synthesis and anticancer activity of new thiopyrano[2,3-d]thiazoles based on 5-hydroxy-1,4-naphthoquinone (juglone).
Ivasechko I, Lozynskyi A, Senkiv J, Roszczenko P, Kozak Y, Finiuk N, Klyuchivska O, Kashchak N, Manko N, Maslyak Z, Lesyk D, Karkhut A, Polovkovych S, Czarnomysy R, Szewczyk O, Kozytskiy A, Karpenko O, Khyluk D, Gzella A, Bielawski K, Bielawska A, Dzubak P, Gurska S, Hajduch M, Stoika R, Lesyk R. Ivasechko I, et al. Among authors: kozytskiy a. Eur J Med Chem. 2023 Apr 5;252:115304. doi: 10.1016/j.ejmech.2023.115304. Epub 2023 Mar 24. Eur J Med Chem. 2023. PMID: 37001390 Free article.
Reductive Recyclization of sp3-Enriched Functionalized Isoxazolines into α-Hydroxy Lactams.
Chalyk BA, Khutorianskyi AV, Vashchenko BV, Danyleiko K, Grynyova A, Osipova AO, Kozytskiy A, Syniuchenko D, Tsymbaliuk A, Gavrilenko KS, Biitseva AV, Volochnyuk DM, Komarov IV, Grygorenko OO. Chalyk BA, et al. Among authors: kozytskiy a. J Org Chem. 2022 Jan 21;87(2):1001-1018. doi: 10.1021/acs.joc.1c02301. Epub 2021 Nov 29. J Org Chem. 2022. PMID: 34843235
Third Generation Buchwald Precatalysts with XPhos and RuPhos: Multigram Scale Synthesis, Solvent-Dependent Isomerization of XPhos Pd G3 and Quality Control by 1H- and 31P-NMR Spectroscopy.
Sotnik SO, Mishchenko AM, Rusanov EB, Kozytskiy AV, Gavrilenko KS, Ryabukhin SV, Volochnyuk DM, Kolotilov SV. Sotnik SO, et al. Among authors: kozytskiy av. Molecules. 2021 Jun 9;26(12):3507. doi: 10.3390/molecules26123507. Molecules. 2021. PMID: 34207506 Free PMC article.
Rapid synthetic approaches to libraries of diversified 1,2-dihydrochromeno[2,3-c]pyrrole-3,9-diones and 3-(2-hydroxyphenyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-ones.
Vydzhak RN, Panchishin SY, Kachaeva MV, Pilyo SG, Moskvina VS, Shablykina OV, Kozytskiy AV, Brovarets VS. Vydzhak RN, et al. Among authors: kozytskiy av. Mol Divers. 2022 Apr;26(2):1115-1128. doi: 10.1007/s11030-021-10234-2. Epub 2021 Jun 4. Mol Divers. 2022. PMID: 34086156 Free PMC article.
Solution to the symmetrical molecule NMR challenge.
Kozytskiy AV. Kozytskiy AV. Anal Bioanal Chem. 2023 Jul;415(16):3053. doi: 10.1007/s00216-023-04733-4. Epub 2023 Jun 22. Anal Bioanal Chem. 2023. PMID: 37347304 No abstract available.
Symmetrical molecule NMR challenge.
Kozytskiy AV. Kozytskiy AV. Anal Bioanal Chem. 2023 Jan;415(1):3-4. doi: 10.1007/s00216-022-04383-y. Epub 2023 Jan 6. Anal Bioanal Chem. 2023. PMID: 36604344 No abstract available.