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A compound directed against S6K1 hampers fat mass expansion and mitigates diet-induced hepatosteatosis.
Lluch A, Veiga SR, Latorre J, Moreno-Navarrete JM, Bonifaci N, Dien Nguyen V, Zhou Y, Höring M, Liebisch G, Olkkonen VM, Llobet-Navas D, Thomas G, Rodríguez-Barrueco R, Fernández-Real JM, Kozma SC, Ortega FJ. Lluch A, et al. Among authors: kozma sc. JCI Insight. 2022 Jul 22;7(14):e150461. doi: 10.1172/jci.insight.150461. JCI Insight. 2022. PMID: 35737463 Free PMC article.
A liaison between mTOR signaling, ribosome biogenesis and cancer.
Gentilella A, Kozma SC, Thomas G. Gentilella A, et al. Among authors: kozma sc. Biochim Biophys Acta. 2015 Jul;1849(7):812-20. doi: 10.1016/j.bbagrm.2015.02.005. Epub 2015 Feb 28. Biochim Biophys Acta. 2015. PMID: 25735853 Free PMC article. Review.
Mitochondrial Complex I Activity Is Required for Maximal Autophagy.
Thomas HE, Zhang Y, Stefely JA, Veiga SR, Thomas G, Kozma SC, Mercer CA. Thomas HE, et al. Among authors: kozma sc. Cell Rep. 2018 Aug 28;24(9):2404-2417.e8. doi: 10.1016/j.celrep.2018.07.101. Cell Rep. 2018. PMID: 30157433 Free PMC article.
EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice.
Arif A, Terenzi F, Potdar AA, Jia J, Sacks J, China A, Halawani D, Vasu K, Li X, Brown JM, Chen J, Kozma SC, Thomas G, Fox PL. Arif A, et al. Among authors: kozma sc. Nature. 2017 Feb 16;542(7641):357-361. doi: 10.1038/nature21380. Epub 2017 Feb 8. Nature. 2017. PMID: 28178239 Free PMC article.
Effect of low doses of actinomycin D on neuroblastoma cell lines.
Cortes CL, Veiga SR, Almacellas E, Hernández-Losa J, Ferreres JC, Kozma SC, Ambrosio S, Thomas G, Tauler A. Cortes CL, et al. Among authors: kozma sc. Mol Cancer. 2016 Jan 4;15:1. doi: 10.1186/s12943-015-0489-8. Mol Cancer. 2016. PMID: 26728659 Free PMC article.
98 results