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Temporal molecular and biological assessment of an erlotinib-resistant lung adenocarcinoma model reveals markers of tumor progression and treatment response.
Weaver Z, Difilippantonio S, Carretero J, Martin PL, El Meskini R, Iacovelli AJ, Gumprecht M, Kulaga A, Guerin T, Schlomer J, Baran M, Kozlov S, McCann T, Mena S, Al-Shahrour F, Alexander D, Wong KK, Van Dyke T. Weaver Z, et al. Among authors: kozlov s. Cancer Res. 2012 Nov 15;72(22):5921-33. doi: 10.1158/0008-5472.CAN-12-0736. Epub 2012 Sep 11. Cancer Res. 2012. PMID: 22969147 Free PMC article.
T Cell-Mediated Antitumor Immunity Cooperatively Induced By TGFβR1 Antagonism and Gemcitabine Counteracts Reformation of the Stromal Barrier in Pancreatic Cancer.
Li D, Schaub N, Guerin TM, Bapiro TE, Richards FM, Chen V, Talsania K, Kumar P, Gilbert DJ, Schlomer JJ, Kim SJ, Sorber R, Teper Y, Bautista W, Palena C, Ock CY, Jodrell DI, Pate N, Mehta M, Zhao Y, Kozlov S, Rudloff U. Li D, et al. Among authors: kozlov s. Mol Cancer Ther. 2021 Oct;20(10):1926-1940. doi: 10.1158/1535-7163.MCT-20-0620. Epub 2021 Aug 10. Mol Cancer Ther. 2021. PMID: 34376576 Free PMC article.
Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer.
Vilimas T, Wang AQ, Patnaik S, Hughes EA, Singleton MD, Knotts Z, Li D, Frankowski K, Schlomer JJ, Guerin TM, Springer S, Drennan C, Dextras C, Wang C, Gilbert D, Southall N, Ferrer M, Huang S, Kozlov S, Marugan J, Xu X, Rudloff U. Vilimas T, et al. Among authors: kozlov s. Cancer Chemother Pharmacol. 2018 Dec;82(6):1067-1080. doi: 10.1007/s00280-018-3699-0. Epub 2018 Oct 10. Cancer Chemother Pharmacol. 2018. PMID: 30306263 Free PMC article.
Novel Humanized Mesothelin-Expressing Genetically Engineered Mouse Models Underscore Challenges in Delivery of Complex Therapeutics to Pancreatic Cancers.
Hagerty B, O'Sullivan TN, Zhang X, Collins NK, Custer Lawrence W, Bassel LL, Pate N, Xu J, Guerin TM, Kozlov S, Alewine C. Hagerty B, et al. Among authors: kozlov s. Mol Cancer Ther. 2021 Oct;20(10):2082-2092. doi: 10.1158/1535-7163.MCT-21-0017. Epub 2021 Jul 26. Mol Cancer Ther. 2021. PMID: 34315768 Free PMC article.
Evolutionary etiology of high-grade astrocytomas.
Song Y, Zhang Q, Kutlu B, Difilippantonio S, Bash R, Gilbert D, Yin C, O'Sullivan TN, Yang C, Kozlov S, Bullitt E, McCarthy KD, Kafri T, Louis DN, Miller CR, Hood L, Van Dyke T. Song Y, et al. Among authors: kozlov s. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17933-8. doi: 10.1073/pnas.1317026110. Epub 2013 Oct 10. Proc Natl Acad Sci U S A. 2013. PMID: 24114272 Free PMC article.
Synergistic targeted inhibition of MEK and dual PI3K/mTOR diminishes viability and inhibits tumor growth of canine melanoma underscoring its utility as a preclinical model for human mucosal melanoma.
Wei BR, Michael HT, Halsey CH, Peer CJ, Adhikari A, Dwyer JE, Hoover SB, El Meskini R, Kozlov S, Weaver Ohler Z, Figg WD, Merlino G, Simpson RM. Wei BR, et al. Among authors: kozlov s. Pigment Cell Melanoma Res. 2016 Nov;29(6):643-655. doi: 10.1111/pcmr.12512. Epub 2016 Sep 22. Pigment Cell Melanoma Res. 2016. PMID: 27463366 Free PMC article.
Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.
Sherman MH, Yu RT, Engle DD, Ding N, Atkins AR, Tiriac H, Collisson EA, Connor F, Van Dyke T, Kozlov S, Martin P, Tseng TW, Dawson DW, Donahue TR, Masamune A, Shimosegawa T, Apte MV, Wilson JS, Ng B, Lau SL, Gunton JE, Wahl GM, Hunter T, Drebin JA, O'Dwyer PJ, Liddle C, Tuveson DA, Downes M, Evans RM. Sherman MH, et al. Among authors: kozlov s. Cell. 2014 Sep 25;159(1):80-93. doi: 10.1016/j.cell.2014.08.007. Cell. 2014. PMID: 25259922 Free PMC article.
LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies.
O'Neill MJ, Chan K, Jaynes JM, Knotts Z, Xu X, Abisoye-Ogunniyan A, Guerin T, Schlomer J, Li D, Cary JW, Rajasekaran K, Yates C, Kozlov S, Andresson T, Rudloff U. O'Neill MJ, et al. Among authors: kozlov s. J Pharm Biomed Anal. 2020 Mar 20;181:113093. doi: 10.1016/j.jpba.2020.113093. Epub 2020 Jan 2. J Pharm Biomed Anal. 2020. PMID: 31931447 Free PMC article.
Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma.
Hackett CS, Quigley DA, Wong RA, Chen J, Cheng C, Song YK, Wei JS, Pawlikowska L, Bao Y, Goldenberg DD, Nguyen K, Gustafson WC, Rallapalli SK, Cho YJ, Cook JM, Kozlov S, Mao JH, Van Dyke T, Kwok PY, Khan J, Balmain A, Fan Q, Weiss WA. Hackett CS, et al. Among authors: kozlov s. Cell Rep. 2014 Nov 6;9(3):1034-46. doi: 10.1016/j.celrep.2014.09.046. Epub 2014 Oct 23. Cell Rep. 2014. PMID: 25437558 Free PMC article.
573 results