Kozlenkov A - Search Results

1

Divergent single cell transcriptome and epigenome alterations in ALS and FTD patients with C9orf72 mutation.

Li J, Jaiswal MK, Chien JF, Kozlenkov A, Jung J, Zhou P, Gardashli M, Pregent LJ, Engelberg-Cook E, Dickson DW, Belzil VV, Mukamel EA, Dracheva S. Li J, et al. Among authors: kozlenkov a. Nat Commun. 2023 Sep 15;14(1):5714. doi: 10.1038/s41467-023-41033-y. Nat Commun. 2023. PMID: 37714849 Free PMC article.

2

A unique role for DNA (hydroxy)methylation in epigenetic regulation of human inhibitory neurons.

Kozlenkov A, Li J, Apontes P, Hurd YL, Byne WM, Koonin EV, Wegner M, Mukamel EA, Dracheva S. Kozlenkov A, et al. Sci Adv. 2018 Sep 26;4(9):eaau6190. doi: 10.1126/sciadv.aau6190. eCollection 2018 Sep. Sci Adv. 2018. PMID: 30263963 Free PMC article.

3

Evolution of regulatory signatures in primate cortical neurons at cell-type resolution.

Kozlenkov A, Vermunt MW, Apontes P, Li J, Hao K, Sherwood CC, Hof PR, Ely JJ, Wegner M, Mukamel EA, Creyghton MP, Koonin EV, Dracheva S. Kozlenkov A, et al. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28422-28432. doi: 10.1073/pnas.2011884117. Epub 2020 Oct 27. Proc Natl Acad Sci U S A. 2020. PMID: 33109720 Free PMC article.

4

Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons.

Hauberg ME, Creus-Muncunill J, Bendl J, Kozlenkov A, Zeng B, Corwin C, Chowdhury S, Kranz H, Hurd YL, Wegner M, Børglum AD, Dracheva S, Ehrlich ME, Fullard JF, Roussos P. Hauberg ME, et al. Among authors: kozlenkov a. Nat Commun. 2020 Nov 4;11(1):5581. doi: 10.1038/s41467-020-19319-2. Nat Commun. 2020. PMID: 33149216 Free PMC article.

5

Novel method of isolating nuclei of human oligodendrocyte precursor cells reveals substantial developmental changes in gene expression and H3K27ac histone modification.

Kozlenkov A, Vadukapuram R, Zhou P, Fam P, Wegner M, Dracheva S. Kozlenkov A, et al. Glia. 2024 Jan;72(1):69-89. doi: 10.1002/glia.24462. Epub 2023 Sep 15. Glia. 2024. PMID: 37712493

6

Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum.

Lu AT, Hannon E, Levine ME, Hao K, Crimmins EM, Lunnon K, Kozlenkov A, Mill J, Dracheva S, Horvath S. Lu AT, et al. Among authors: kozlenkov a. Nat Commun. 2016 Feb 2;7:10561. doi: 10.1038/ncomms10561. Nat Commun. 2016. PMID: 26830004 Free PMC article.

7

Molecular windows into the human brain for psychiatric disorders.

Egervari G, Kozlenkov A, Dracheva S, Hurd YL. Egervari G, et al. Among authors: kozlenkov a. Mol Psychiatry. 2019 May;24(5):653-673. doi: 10.1038/s41380-018-0125-2. Epub 2018 Jun 28. Mol Psychiatry. 2019. PMID: 29955163 Free PMC article. Review.

8

Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders.

Hu B, Won H, Mah W, Park RB, Kassim B, Spiess K, Kozlenkov A, Crowley CA, Pochareddy S; PsychENCODE Consortium; Li Y, Dracheva S, Sestan N, Akbarian S, Geschwind DH. Hu B, et al. Among authors: kozlenkov a. Nat Commun. 2021 Jun 25;12(1):3968. doi: 10.1038/s41467-021-24243-0. Nat Commun. 2021. PMID: 34172755 Free PMC article.

9

Substantial DNA methylation differences between two major neuronal subtypes in human brain.

Kozlenkov A, Wang M, Roussos P, Rudchenko S, Barbu M, Bibikova M, Klotzle B, Dwork AJ, Zhang B, Hurd YL, Koonin EV, Wegner M, Dracheva S. Kozlenkov A, et al. Nucleic Acids Res. 2016 Apr 7;44(6):2593-612. doi: 10.1093/nar/gkv1304. Epub 2015 Nov 26. Nucleic Acids Res. 2016. PMID: 26612861 Free PMC article.

10

Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites.

Kozlenkov A, Roussos P, Timashpolsky A, Barbu M, Rudchenko S, Bibikova M, Klotzle B, Byne W, Lyddon R, Di Narzo AF, Hurd YL, Koonin EV, Dracheva S. Kozlenkov A, et al. Nucleic Acids Res. 2014 Jan;42(1):109-27. doi: 10.1093/nar/gkt838. Epub 2013 Sep 20. Nucleic Acids Res. 2014. PMID: 24057217 Free PMC article.

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