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A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection.
Wright SC, Kozielewicz P, Kowalski-Jahn M, Petersen J, Bowin CF, Slodkowicz G, Marti-Solano M, Rodríguez D, Hot B, Okashah N, Strakova K, Valnohova J, Babu MM, Lambert NA, Carlsson J, Schulte G. Wright SC, et al. Among authors: kozielewicz p. Nat Commun. 2019 Feb 8;10(1):667. doi: 10.1038/s41467-019-08630-2. Nat Commun. 2019. PMID: 30737406 Free PMC article.
Molecular Pharmacology of Class F Receptor Activation.
Kozielewicz P, Turku A, Schulte G. Kozielewicz P, et al. Mol Pharmacol. 2020 Feb;97(2):62-71. doi: 10.1124/mol.119.117986. Epub 2019 Oct 7. Mol Pharmacol. 2020. PMID: 31591260 Review.
THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein-coupled receptors.
Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. Alexander SPH, et al. Br J Pharmacol. 2019 Dec;176 Suppl 1(Suppl 1):S21-S141. doi: 10.1111/bph.14748. Br J Pharmacol. 2019. PMID: 31710717 Free PMC article. Review.
Structural insight into small molecule action on Frizzleds.
Kozielewicz P, Turku A, Bowin CF, Petersen J, Valnohova J, Cañizal MCA, Ono Y, Inoue A, Hoffmann C, Schulte G. Kozielewicz P, et al. Nat Commun. 2020 Jan 21;11(1):414. doi: 10.1038/s41467-019-14149-3. Nat Commun. 2020. PMID: 31964872 Free PMC article.
eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled.
Wesslowski J, Kozielewicz P, Wang X, Cui H, Schihada H, Kranz D, Karuna M P, Levkin P, Gross JC, Boutros M, Schulte G, Davidson G. Wesslowski J, et al. Among authors: kozielewicz p. J Biol Chem. 2020 Jun 26;295(26):8759-8774. doi: 10.1074/jbc.RA120.012892. Epub 2020 May 7. J Biol Chem. 2020. PMID: 32381507 Free PMC article.
Geissospermiculatine, a New Alkaloid from Geissospermum reticulatum Bark.
Sajkowska-Kozielewicz JJ, Kozielewicz P, Makarova K, Stocki M, Barnes NM, Paradowska K. Sajkowska-Kozielewicz JJ, et al. Among authors: kozielewicz p. Molecules. 2020 Dec 31;26(1):143. doi: 10.3390/molecules26010143. Molecules. 2020. PMID: 33396182 Free PMC article.
26 results