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Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis.
Wirka RC, Wagh D, Paik DT, Pjanic M, Nguyen T, Miller CL, Kundu R, Nagao M, Coller J, Koyano TK, Fong R, Woo YJ, Liu B, Montgomery SB, Wu JC, Zhu K, Chang R, Alamprese M, Tallquist MD, Kim JB, Quertermous T. Wirka RC, et al. Among authors: koyano tk. Nat Med. 2019 Aug;25(8):1280-1289. doi: 10.1038/s41591-019-0512-5. Epub 2019 Jul 29. Nat Med. 2019. PMID: 31359001 Free PMC article.
Modeling conduit choice for valve-sparing aortic root replacement on biomechanics with a 3-dimensional-printed heart simulator.
Paulsen MJ, Kasinpila P, Imbrie-Moore AM, Wang H, Hironaka CE, Koyano TK, Fong R, Chiu P, Goldstone AB, Steele AN, Stapleton LM, Ma M, Woo YJ. Paulsen MJ, et al. Among authors: koyano tk. J Thorac Cardiovasc Surg. 2019 Aug;158(2):392-403. doi: 10.1016/j.jtcvs.2018.10.145. Epub 2018 Nov 15. J Thorac Cardiovasc Surg. 2019. PMID: 30745047 Free article.
Divergent effects of canonical and non-canonical TGF-β signalling on mixed contractile-synthetic smooth muscle cell phenotype in human Marfan syndrome aortic root aneurysms.
Pedroza AJ, Koyano T, Trojan J, Rubin A, Palmon I, Jaatinen K, Burdon G, Chang P, Tashima Y, Cui JZ, Berry G, Iosef C, Fischbein MP. Pedroza AJ, et al. J Cell Mol Med. 2020 Feb;24(3):2369-2383. doi: 10.1111/jcmm.14921. Epub 2019 Dec 30. J Cell Mol Med. 2020. PMID: 31886938 Free PMC article.
Donors after circulatory death heart trial.
Shudo Y, Benjamin-Addy R, Koyano TK, Hiesinger W, MacArthur JW, Woo YJ. Shudo Y, et al. Among authors: koyano tk. Future Cardiol. 2021 Jan;17(1):11-17. doi: 10.2217/fca-2020-0070. Epub 2020 Jul 6. Future Cardiol. 2021. PMID: 32628044
Human Coronary Plaque T Cells Are Clonal and Cross-React to Virus and Self.
Chowdhury RR, D'Addabbo J, Huang X, Veizades S, Sasagawa K, Louis DM, Cheng P, Sokol J, Jensen A, Tso A, Shankar V, Wendel BS, Bakerman I, Liang G, Koyano T, Fong R, Nau AN, Ahmad H, Gopakumar J, Wirka R, Lee AS, Boyd J, Woo YJ, Quertermous T, Gulati GS, Jaiswal S, Chien YH, Chan CKF, Davis MM, Nguyen PK. Chowdhury RR, et al. Circ Res. 2022 May 13;130(10):1510-1530. doi: 10.1161/CIRCRESAHA.121.320090. Epub 2022 Apr 18. Circ Res. 2022. PMID: 35430876 Free PMC article.
Enhanced caspase activity contributes to aortic wall remodeling and early aneurysm development in a murine model of Marfan syndrome.
Emrich FC, Okamura H, Dalal AR, Penov K, Merk DR, Raaz U, Hennigs JK, Chin JT, Miller MO, Pedroza AJ, Craig JK, Koyano TK, Blankenberg FG, Connolly AJ, Mohr FW, Alvira CM, Rabinovitch M, Fischbein MP. Emrich FC, et al. Among authors: koyano tk. Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):146-54. doi: 10.1161/ATVBAHA.114.304364. Epub 2014 Oct 30. Arterioscler Thromb Vasc Biol. 2015. PMID: 25359856
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