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Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche.
Krohn-Grimberghe M, Mitchell MJ, Schloss MJ, Khan OF, Courties G, Guimaraes PPG, Rohde D, Cremer S, Kowalski PS, Sun Y, Tan M, Webster J, Wang K, Iwamoto Y, Schmidt SP, Wojtkiewicz GR, Nayar R, Frodermann V, Hulsmans M, Chung A, Hoyer FF, Swirski FK, Langer R, Anderson DG, Nahrendorf M. Krohn-Grimberghe M, et al. Among authors: kowalski ps. Nat Biomed Eng. 2020 Nov;4(11):1076-1089. doi: 10.1038/s41551-020-00623-7. Epub 2020 Oct 5. Nat Biomed Eng. 2020. PMID: 33020600 Free PMC article.
Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes.
Gerashchenko MV, Nesterchuk MV, Smekalova EM, Paulo JA, Kowalski PS, Akulich KA, Bogorad R, Dmitriev SE, Gygi S, Zatsepin T, Anderson DG, Gladyshev VN, Koteliansky VE. Gerashchenko MV, et al. Among authors: kowalski ps. Sci Rep. 2020 Sep 23;10(1):15473. doi: 10.1038/s41598-020-72399-4. Sci Rep. 2020. PMID: 32968084 Free PMC article.
Long-term implant fibrosis prevention in rodents and non-human primates using crystallized drug formulations.
Farah S, Doloff JC, Müller P, Sadraei A, Han HJ, Olafson K, Vyas K, Tam HH, Hollister-Lock J, Kowalski PS, Griffin M, Meng A, McAvoy M, Graham AC, McGarrigle J, Oberholzer J, Weir GC, Greiner DL, Langer R, Anderson DG. Farah S, et al. Among authors: kowalski ps. Nat Mater. 2019 Aug;18(8):892-904. doi: 10.1038/s41563-019-0377-5. Epub 2019 Jun 24. Nat Mater. 2019. PMID: 31235902 Free PMC article.
mRNA Delivery for Therapeutic Anti-HER2 Antibody Expression In Vivo.
Rybakova Y, Kowalski PS, Huang Y, Gonzalez JT, Heartlein MW, DeRosa F, Delcassian D, Anderson DG. Rybakova Y, et al. Among authors: kowalski ps. Mol Ther. 2019 Aug 7;27(8):1415-1423. doi: 10.1016/j.ymthe.2019.05.012. Epub 2019 May 18. Mol Ther. 2019. PMID: 31160223 Free PMC article.
28 results