Kovanen PE - Search Results

1

T-cell development and function are modulated by dual specificity phosphatase DUSP5.

Kovanen PE, Bernard J, Al-Shami A, Liu C, Bollenbacher-Reilley J, Young L, Pise-Masison C, Spolski R, Leonard WJ. Kovanen PE, et al. J Biol Chem. 2008 Jun 20;283(25):17362-9. doi: 10.1074/jbc.M709887200. Epub 2008 Apr 21. J Biol Chem. 2008. PMID: 18430737 Free PMC article.

2

Analysis of gamma c-family cytokine target genes. Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling.

Kovanen PE, Rosenwald A, Fu J, Hurt EM, Lam LT, Giltnane JM, Wright G, Staudt LM, Leonard WJ. Kovanen PE, et al. J Biol Chem. 2003 Feb 14;278(7):5205-13. doi: 10.1074/jbc.M209015200. Epub 2002 Nov 14. J Biol Chem. 2003. PMID: 12435740 Free article.

3

IL-2 negatively regulates IL-7 receptor alpha chain expression in activated T lymphocytes.

Xue HH, Kovanen PE, Pise-Masison CA, Berg M, Radovich MF, Brady JN, Leonard WJ. Xue HH, et al. Among authors: kovanen pe. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13759-64. doi: 10.1073/pnas.212214999. Epub 2002 Sep 27. Proc Natl Acad Sci U S A. 2002. PMID: 12354940 Free PMC article.

4

Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma.

Kelly JA, Spolski R, Kovanen PE, Suzuki T, Bollenbacher J, Pise-Masison CA, Radonovich MF, Lee S, Jenkins NA, Copeland NG, Morse HC 3rd, Leonard WJ. Kelly JA, et al. Among authors: kovanen pe. J Exp Med. 2003 Jul 7;198(1):79-89. doi: 10.1084/jem.20021548. Epub 2003 Jun 30. J Exp Med. 2003. PMID: 12835478 Free PMC article.

5

Cytokines and immunodeficiency diseases: critical roles of the gamma(c)-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways.

Kovanen PE, Leonard WJ. Kovanen PE, et al. Immunol Rev. 2004 Dec;202:67-83. doi: 10.1111/j.0105-2896.2004.00203.x. Immunol Rev. 2004. PMID: 15546386 Review.

6

Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function.

Zeng R, Spolski R, Finkelstein SE, Oh S, Kovanen PE, Hinrichs CS, Pise-Masison CA, Radonovich MF, Brady JN, Restifo NP, Berzofsky JA, Leonard WJ. Zeng R, et al. Among authors: kovanen pe. J Exp Med. 2005 Jan 3;201(1):139-48. doi: 10.1084/jem.20041057. J Exp Med. 2005. PMID: 15630141 Free PMC article.

7

Global analysis of IL-2 target genes: identification of chromosomal clusters of expressed genes.

Kovanen PE, Young L, Al-Shami A, Rovella V, Pise-Masison CA, Radonovich MF, Powell J, Fu J, Brady JN, Munson PJ, Leonard WJ. Kovanen PE, et al. Int Immunol. 2005 Aug;17(8):1009-21. doi: 10.1093/intimm/dxh283. Epub 2005 Jun 24. Int Immunol. 2005. PMID: 15980098

8

Inhibitors keep cytokines in check.

Kovanen PE, Leonard WJ. Kovanen PE, et al. Curr Biol. 1999 Dec 2;9(23):R899-902. doi: 10.1016/s0960-9822(00)80079-2. Curr Biol. 1999. PMID: 10607559 Free article.

9

JAB/SOCS1/SSI-1 is an interleukin-2-induced inhibitor of IL-2 signaling.

Sporri B, Kovanen PE, Sasaki A, Yoshimura A, Leonard WJ. Sporri B, et al. Among authors: kovanen pe. Blood. 2001 Jan 1;97(1):221-6. doi: 10.1182/blood.v97.1.221. Blood. 2001. PMID: 11133764 Free article.

10

Interleukin-4-induced transcriptional activation by stat6 involves multiple serine/threonine kinase pathways and serine phosphorylation of stat6.

Pesu M, Takaluoma K, Aittomäki S, Lagerstedt A, Saksela K, Kovanen PE, Silvennoinen O. Pesu M, et al. Among authors: kovanen pe. Blood. 2000 Jan 15;95(2):494-502. Blood. 2000. PMID: 10627454 Free article.

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