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Mitochondrial complex II in intestinal epithelial cells regulates T cell-mediated immunopathology.
Fujiwara H, Seike K, Brooks MD, Mathew AV, Kovalenko I, Pal A, Lee HJ, Peltier D, Kim S, Liu C, Oravecz-Wilson K, Li L, Sun Y, Byun J, Maeda Y, Wicha MS, Saunders TL, Rehemtulla A, Lyssiotis CA, Pennathur S, Reddy P. Fujiwara H, et al. Among authors: kovalenko i. Nat Immunol. 2021 Nov;22(11):1440-1451. doi: 10.1038/s41590-021-01048-3. Epub 2021 Oct 22. Nat Immunol. 2021. PMID: 34686860 Free PMC article.
Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma.
Schofield HK, Zeller J, Espinoza C, Halbrook CJ, Del Vecchio A, Magnuson B, Fabo T, Cali Daylan AE, Kovalenko I, Lee HJ, Yan W, Feng Y, Karim SA, Kremer DM, Kumar-Sinha C, Lyssiotis CA, Ljungman M, Morton JP, Galbán S, Fearon ER, Pasca di Magliano M. Schofield HK, et al. Among authors: kovalenko i. JCI Insight. 2018 Jan 25;3(2):e97422. doi: 10.1172/jci.insight.97422. eCollection 2018 Jan 25. JCI Insight. 2018. PMID: 29367463 Free PMC article.
Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer.
Halbrook CJ, Pontious C, Kovalenko I, Lapienyte L, Dreyer S, Lee HJ, Thurston G, Zhang Y, Lazarus J, Sajjakulnukit P, Hong HS, Kremer DM, Nelson BS, Kemp S, Zhang L, Chang D, Biankin A, Shi J, Frankel TL, Crawford HC, Morton JP, Pasca di Magliano M, Lyssiotis CA. Halbrook CJ, et al. Among authors: kovalenko i. Cell Metab. 2019 Jun 4;29(6):1390-1399.e6. doi: 10.1016/j.cmet.2019.02.001. Epub 2019 Feb 28. Cell Metab. 2019. PMID: 30827862 Free PMC article.
Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy.
Nelson BS, Lin L, Kremer DM, Sousa CM, Cotta-Ramusino C, Myers A, Ramos J, Gao T, Kovalenko I, Wilder-Romans K, Dresser J, Davis M, Lee HJ, Nwosu ZC, Campit S, Mashadova O, Nicolay BN, Tolstyka ZP, Halbrook CJ, Chandrasekaran S, Asara JM, Crawford HC, Cantley LC, Kimmelman AC, Wahl DR, Lyssiotis CA. Nelson BS, et al. Among authors: kovalenko i. Cancer Metab. 2020 Jan 2;8:1. doi: 10.1186/s40170-019-0202-2. eCollection 2020. Cancer Metab. 2020. PMID: 31908776 Free PMC article.
A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells.
Chefetz I, Grimley E, Yang K, Hong L, Vinogradova EV, Suciu R, Kovalenko I, Karnak D, Morgan CA, Chtcherbinine M, Buchman C, Huddle B, Barraza S, Morgan M, Bernstein KA, Yoon E, Lombard DB, Bild A, Mehta G, Romero I, Chiang CY, Landen C, Cravatt B, Hurley TD, Larsen SD, Buckanovich RJ. Chefetz I, et al. Among authors: kovalenko i. Cell Rep. 2019 Mar 12;26(11):3061-3075.e6. doi: 10.1016/j.celrep.2019.02.032. Cell Rep. 2019. PMID: 30865894 Free PMC article.
TRPC6 channels modulate the response of pancreatic stellate cells to hypoxia.
Nielsen N, Kondratska K, Ruck T, Hild B, Kovalenko I, Schimmelpfennig S, Welzig J, Sargin S, Lindemann O, Christian S, Meuth SG, Prevarskaya N, Schwab A. Nielsen N, et al. Among authors: kovalenko i. Pflugers Arch. 2017 Dec;469(12):1567-1577. doi: 10.1007/s00424-017-2057-0. Epub 2017 Aug 28. Pflugers Arch. 2017. PMID: 28849300
314 results