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Malignant pleural mesothelioma nodules remodel their surroundings to vascularize and grow.
Kovacs I, Bugyik E, Dezso K, Tarnoki-Zach J, Mehes E, Gulyas M, Czirok A, Lang E, Grusch M, Schelch K, Hegedus B, Horvath I, Barany N, Megyesfalvi Z, Tisza A, Lohinai Z, Hoda MA, Hoetzenecker K, Pezzella F, Paku S, Laszlo V, Dome B. Kovacs I, et al. Transl Lung Cancer Res. 2022 Jun;11(6):991-1008. doi: 10.21037/tlcr-21-828. Transl Lung Cancer Res. 2022. PMID: 35832452 Free PMC article.
Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors.
Torok S, Rezeli M, Kelemen O, Vegvari A, Watanabe K, Sugihara Y, Tisza A, Marton T, Kovacs I, Tovari J, Laszlo V, Helbich TH, Hegedus B, Klikovits T, Hoda MA, Klepetko W, Paku S, Marko-Varga G, Dome B. Torok S, et al. Among authors: kovacs i. Theranostics. 2017 Jan 1;7(2):400-412. doi: 10.7150/thno.16767. eCollection 2017. Theranostics. 2017. PMID: 28042343 Free PMC article.
Nintedanib Is Active in Malignant Pleural Mesothelioma Cell Models and Inhibits Angiogenesis and Tumor Growth In Vivo.
Laszlo V, Valko Z, Kovacs I, Ozsvar J, Hoda MA, Klikovits T, Lakatos D, Czirok A, Garay T, Stiglbauer A, Helbich TH, Gröger M, Tovari J, Klepetko W, Pirker C, Grusch M, Berger W, Hilberg F, Hegedus B, Dome B. Laszlo V, et al. Among authors: kovacs i. Clin Cancer Res. 2018 Aug 1;24(15):3729-3740. doi: 10.1158/1078-0432.CCR-17-1507. Epub 2018 May 3. Clin Cancer Res. 2018. PMID: 29724868
The FAK inhibitor BI 853520 inhibits spheroid formation and orthotopic tumor growth in malignant pleural mesothelioma.
Laszlo V, Valko Z, Ozsvar J, Kovacs I, Garay T, Hoda MA, Klikovits T, Stockhammer P, Aigner C, Gröger M, Klepetko W, Berger W, Grusch M, Tovari J, Waizenegger IC, Dome B, Hegedus B. Laszlo V, et al. Among authors: kovacs i. J Mol Med (Berl). 2019 Feb;97(2):231-242. doi: 10.1007/s00109-018-1725-7. Epub 2018 Dec 11. J Mol Med (Berl). 2019. PMID: 30539198 Free PMC article.
Comparative analysis of prognostic histopathologic parameters in subtypes of epithelioid pleural mesothelioma.
Bilecz A, Stockhammer P, Theegarten D, Kern I, Jakopovic M, Samarzija M, Klikovits T, Hoda MA, Döme B, Oberndorfer F, Muellauer L, Fillinger J, Kovács I, Pirker C, Schuler M, Plönes T, Aigner C, Klepetko W, Berger W, Brcic L, Laszlo V, Hegedus B. Bilecz A, et al. Among authors: kovacs i. Histopathology. 2020 Jul;77(1):55-66. doi: 10.1111/his.14105. Epub 2020 May 25. Histopathology. 2020. PMID: 32170970
HDAC Inhibition Induces PD-L1 Expression in a Novel Anaplastic Thyroid Cancer Cell Line.
Hegedűs L, Rittler D, Garay T, Stockhammer P, Kovács I, Döme B, Theurer S, Hager T, Herold T, Kalbourtzis S, Bankfalvi A, Schmid KW, Führer D, Aigner C, Hegedűs B. Hegedűs L, et al. Among authors: kovacs i. Pathol Oncol Res. 2020 Oct;26(4):2523-2535. doi: 10.1007/s12253-020-00834-y. Epub 2020 Jun 26. Pathol Oncol Res. 2020. PMID: 32591993 Free PMC article.
Multicellular contractility contributes to the emergence of mesothelioma nodules.
Tarnoki-Zach J, Stockhammer P, Isai DG, Mehes E, Szeder B, Kovacs I, Bugyik E, Paku S, Berger W, Thomas SM, Neufeld Z, Dome B, Hegedus B, Czirok A. Tarnoki-Zach J, et al. Among authors: kovacs i. Sci Rep. 2020 Nov 18;10(1):20114. doi: 10.1038/s41598-020-76641-x. Sci Rep. 2020. PMID: 33208866 Free PMC article.
Apelin promotes blood and lymph vessel formation and the growth of melanoma lung metastasis.
Berta J, Török S, Tárnoki-Zách J, Drozdovszky O, Tóvári J, Paku S, Kovács I, Czirók A, Masri B, Megyesfalvi Z, Oskolás H, Malm J, Ingvar C, Markó-Varga G, Döme B, László V. Berta J, et al. Among authors: kovacs i. Sci Rep. 2021 Mar 11;11(1):5798. doi: 10.1038/s41598-021-85162-0. Sci Rep. 2021. PMID: 33707612 Free PMC article.
Dual targeting of BCL-2 and MCL-1 in the presence of BAX breaks venetoclax resistance in human small cell lung cancer.
Valko Z, Megyesfalvi Z, Schwendenwein A, Lang C, Paku S, Barany N, Ferencz B, Horvath-Rozsas A, Kovacs I, Schlegl E, Pozonec V, Boettiger K, Rezeli M, Marko-Varga G, Renyi-Vamos F, Hoda MA, Klikovits T, Hoetzenecker K, Grusch M, Laszlo V, Dome B, Schelch K. Valko Z, et al. Among authors: kovacs i. Br J Cancer. 2023 May;128(10):1850-1861. doi: 10.1038/s41416-023-02219-9. Epub 2023 Mar 14. Br J Cancer. 2023. PMID: 36918717 Free PMC article.
673 results