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General toxicity assessment of the novel aldose reductase inhibitor cemtirestat.
Prnová MŠ, Račková L, Kováčiková L, Balleková J, Viskupičová J, Micháliková S, Taşkoparan B, Elmazoğlu Z, Rižner TL, Karasu C, Banerjee S, Štefek M. Prnová MŠ, et al. Among authors: kovacikova l. Interdiscip Toxicol. 2019 Nov;12(3):120-128. doi: 10.2478/intox-2019-0014. Epub 2020 Feb 20. Interdiscip Toxicol. 2019. PMID: 32210700 Free PMC article.
Triglyceride-lowering effect of the aldose reductase inhibitor cemtirestat-another factor that may contribute to attenuation of symptoms of peripheral neuropathy in STZ-diabetic rats.
Prnova MS, Kovacikova L, Svik K, Bezek S, Elmazoğlu Z, Karasu C, Stefek M. Prnova MS, et al. Among authors: kovacikova l. Naunyn Schmiedebergs Arch Pharmacol. 2020 Apr;393(4):651-661. doi: 10.1007/s00210-019-01769-1. Epub 2019 Dec 5. Naunyn Schmiedebergs Arch Pharmacol. 2020. PMID: 31802170
Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity.
Hlaváč M, Kováčiková L, Prnová MŠ, Šramel P, Addová G, Májeková M, Hanquet G, Boháč A, Štefek M. Hlaváč M, et al. Among authors: kovacikova l. J Med Chem. 2020 Jan 9;63(1):369-381. doi: 10.1021/acs.jmedchem.9b01747. Epub 2019 Dec 30. J Med Chem. 2020. PMID: 31820975
Antioxidant Mechanisms in the Neuroprotective Action of Cemtirestat: Studies in Chemical Models, Liposomes and Rat Brain Cortical Slices.
Soltesova Prnova M, Medina-Campos ON, Pedraza-Chaverri J, Colín-González AL, Piedra-García F, Rangel-López E, Kovacikova L, Ceylan A, Karasu C, Santamaria A, Stefek M. Soltesova Prnova M, et al. Among authors: kovacikova l. Neuroscience. 2020 Sep 1;443:206-217. doi: 10.1016/j.neuroscience.2020.07.014. Epub 2020 Jul 16. Neuroscience. 2020. PMID: 32681927
56 results