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A Chemical Probe for the ATAD2 Bromodomain.
Bamborough P, Chung CW, Demont EH, Furze RC, Bannister AJ, Che KH, Diallo H, Douault C, Grandi P, Kouzarides T, Michon AM, Mitchell DJ, Prinjha RK, Rau C, Robson S, Sheppard RJ, Upton R, Watson RJ. Bamborough P, et al. Among authors: kouzarides t. Angew Chem Int Ed Engl. 2016 Sep 12;55(38):11382-6. doi: 10.1002/anie.201603928. Epub 2016 Aug 17. Angew Chem Int Ed Engl. 2016. PMID: 27530368 Free PMC article.
Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition.
Theodoulou NH, Bamborough P, Bannister AJ, Becher I, Bit RA, Che KH, Chung CW, Dittmann A, Drewes G, Drewry DH, Gordon L, Grandi P, Leveridge M, Lindon M, Michon AM, Molnar J, Robson SC, Tomkinson NC, Kouzarides T, Prinjha RK, Humphreys PG. Theodoulou NH, et al. Among authors: kouzarides t. J Med Chem. 2016 Feb 25;59(4):1425-39. doi: 10.1021/acs.jmedchem.5b00256. Epub 2015 Apr 30. J Med Chem. 2016. PMID: 25856009 Free PMC article.
Reversing histone methylation.
Bannister AJ, Kouzarides T. Bannister AJ, et al. Among authors: kouzarides t. Nature. 2005 Aug 25;436(7054):1103-6. doi: 10.1038/nature04048. Nature. 2005. PMID: 16121170 Review.
Regulation of chromatin by histone modifications.
Bannister AJ, Kouzarides T. Bannister AJ, et al. Among authors: kouzarides t. Cell Res. 2011 Mar;21(3):381-95. doi: 10.1038/cr.2011.22. Epub 2011 Feb 15. Cell Res. 2011. PMID: 21321607 Free PMC article. Review.
Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy.
Picaud S, Fedorov O, Thanasopoulou A, Leonards K, Jones K, Meier J, Olzscha H, Monteiro O, Martin S, Philpott M, Tumber A, Filippakopoulos P, Yapp C, Wells C, Che KH, Bannister A, Robson S, Kumar U, Parr N, Lee K, Lugo D, Jeffrey P, Taylor S, Vecellio ML, Bountra C, Brennan PE, O'Mahony A, Velichko S, Müller S, Hay D, Daniels DL, Urh M, La Thangue NB, Kouzarides T, Prinjha R, Schwaller J, Knapp S. Picaud S, et al. Among authors: kouzarides t. Cancer Res. 2015 Dec 1;75(23):5106-5119. doi: 10.1158/0008-5472.CAN-15-0236. Epub 2015 Nov 9. Cancer Res. 2015. PMID: 26552700 Free PMC article.
Histone methylation: dynamic or static?
Bannister AJ, Schneider R, Kouzarides T. Bannister AJ, et al. Among authors: kouzarides t. Cell. 2002 Jun 28;109(7):801-6. doi: 10.1016/s0092-8674(02)00798-5. Cell. 2002. PMID: 12110177 Free article. Review.
Unsafe SETs: histone lysine methyltransferases and cancer.
Schneider R, Bannister AJ, Kouzarides T. Schneider R, et al. Among authors: kouzarides t. Trends Biochem Sci. 2002 Aug;27(8):396-402. doi: 10.1016/s0968-0004(02)02141-2. Trends Biochem Sci. 2002. PMID: 12151224 Review.
Direct binding of INHAT to H3 tails disrupted by modifications.
Schneider R, Bannister AJ, Weise C, Kouzarides T. Schneider R, et al. Among authors: kouzarides t. J Biol Chem. 2004 Jun 4;279(23):23859-62. doi: 10.1074/jbc.C400151200. Epub 2004 Apr 19. J Biol Chem. 2004. PMID: 15100215 Free article.
200 results