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A single intramuscular vaccination of mice with the HSV-1 VC2 virus with mutations in the glycoprotein K and the membrane protein UL20 confers full protection against lethal intravaginal challenge with virulent HSV-1 and HSV-2 strains.
Stanfield BA, Stahl J, Chouljenko VN, Subramanian R, Charles AS, Saied AA, Walker JD, Kousoulas KG. Stanfield BA, et al. Among authors: kousoulas kg. PLoS One. 2014 Oct 28;9(10):e109890. doi: 10.1371/journal.pone.0109890. eCollection 2014. PLoS One. 2014. PMID: 25350288 Free PMC article.
Vaccination of rhesus macaques with the live-attenuated HSV-1 vaccine VC2 stimulates the proliferation of mucosal T cells and germinal center responses resulting in sustained production of highly neutralizing antibodies.
Stanfield BA, Pahar B, Chouljenko VN, Veazey R, Kousoulas KG. Stanfield BA, et al. Among authors: kousoulas kg. Vaccine. 2017 Jan 23;35(4):536-543. doi: 10.1016/j.vaccine.2016.12.018. Epub 2016 Dec 22. Vaccine. 2017. PMID: 28017425 Free article.
Intramuscular Immunization of Mice with the Live-Attenuated Herpes Simplex Virus 1 Vaccine Strain VC2 Expressing Equine Herpesvirus 1 (EHV-1) Glycoprotein D Generates Anti-EHV-1 Immune Responses in Mice.
Liu SA, Stanfield BA, Chouljenko VN, Naidu S, Langohr I, Del Piero F, Ferracone J, Roy AA, Kousoulas KG. Liu SA, et al. Among authors: kousoulas kg. J Virol. 2017 May 26;91(12):e02445-16. doi: 10.1128/JVI.02445-16. Print 2017 Jun 15. J Virol. 2017. PMID: 28404844 Free PMC article.
152 results