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Alboserpin, a factor Xa inhibitor from the mosquito vector of yellow fever, binds heparin and membrane phospholipids and exhibits antithrombotic activity.
Calvo E, Mizurini DM, Sá-Nunes A, Ribeiro JM, Andersen JF, Mans BJ, Monteiro RQ, Kotsyfakis M, Francischetti IM. Calvo E, et al. Among authors: kotsyfakis m. J Biol Chem. 2011 Aug 12;286(32):27998-8010. doi: 10.1074/jbc.M111.247924. Epub 2011 Jun 14. J Biol Chem. 2011. PMID: 21673107 Free PMC article.
Defibrotide interferes with several steps of the coagulation-inflammation cycle and exhibits therapeutic potential to treat severe malaria.
Francischetti IM, Oliveira CJ, Ostera GR, Yager SB, Debierre-Grockiego F, Carregaro V, Jaramillo-Gutierrez G, Hume JC, Jiang L, Moretz SE, Lin CK, Ribeiro JM, Long CA, Vickers BK, Schwarz RT, Seydel KB, Iacobelli M, Ackerman HC, Srinivasan P, Gomes RB, Wang X, Monteiro RQ, Kotsyfakis M, Sá-Nunes A, Waisberg M. Francischetti IM, et al. Among authors: kotsyfakis m. Arterioscler Thromb Vasc Biol. 2012 Mar;32(3):786-98. doi: 10.1161/ATVBAHA.111.240291. Epub 2011 Nov 23. Arterioscler Thromb Vasc Biol. 2012. PMID: 22116094 Free PMC article.
Tick salivary secretion as a source of antihemostatics.
Chmelar J, Calvo E, Pedra JH, Francischetti IM, Kotsyfakis M. Chmelar J, et al. Among authors: kotsyfakis m. J Proteomics. 2012 Jul 16;75(13):3842-54. doi: 10.1016/j.jprot.2012.04.026. Epub 2012 Apr 27. J Proteomics. 2012. PMID: 22564820 Free PMC article. Review.
91 results