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Classic Phytochemical Antioxidant and Lipoxygenase Inhibitor, Nordihydroguaiaretic Acid, Activates Phospholipase D through Oxidant Signaling and Tyrosine Phosphorylation Leading to Cytotoxicity in Lung Vascular Endothelial Cells.
Parinandi NL, Liaugminas A, Oliver PJ, Varadharaj S, Yenigalla A, Elliott AC, Arutla S, Campbell SJ, Kotha SR, Sherwani SI, Kutala VK, McDaniel JC, Maddipati KR, Kuppusamy P, Hund TJ. Parinandi NL, et al. Among authors: kotha sr. Cell Biochem Biophys. 2023 Jun;81(2):205-229. doi: 10.1007/s12013-023-01128-1. Epub 2023 Feb 23. Cell Biochem Biophys. 2023. PMID: 36820994
Adiponectin protects against hyperoxic lung injury and vascular leak.
Sliman SM, Patel RB, Cruff JP, Kotha SR, Newland CA, Schrader CA, Sherwani SI, Gurney TO, Magalang UJ, Parinandi NL. Sliman SM, et al. Among authors: kotha sr. Cell Biochem Biophys. 2013 Nov;67(2):399-414. doi: 10.1007/s12013-011-9330-1. Cell Biochem Biophys. 2013. PMID: 22183615 Free PMC article.
Pentalinonsterol, a Phytosterol from Pentalinon andrieuxii, is Immunomodulatory through Phospholipase A2 in Macrophages toward its Antileishmanial Action.
Varikuti S, Shelton AB, Kotha SR, Gurney T, Gupta G, Hund TJ, Fuchs JR, Kinghorn AD, Srivastava N, Satoskar AR, Parinandi NL. Varikuti S, et al. Among authors: kotha sr. Cell Biochem Biophys. 2022 Mar;80(1):45-61. doi: 10.1007/s12013-021-01030-8. Epub 2021 Aug 13. Cell Biochem Biophys. 2022. PMID: 34387841
Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine protection.
Sliman SM, Eubank TD, Kotha SR, Kuppusamy ML, Sherwani SI, Butler ES, Kuppusamy P, Roy S, Marsh CB, Stern DM, Parinandi NL. Sliman SM, et al. Among authors: kotha sr. Mol Cell Biochem. 2010 Jan;333(1-2):9-26. doi: 10.1007/s11010-009-0199-x. Epub 2009 Jul 8. Mol Cell Biochem. 2010. PMID: 19585224 Free PMC article.
Pulmonary fibrosis inducer, bleomycin, causes redox-sensitive activation of phospholipase D and cytotoxicity through formation of bioactive lipid signal mediator, phosphatidic acid, in lung microvascular endothelial cells.
Patel RB, Kotha SR, Sherwani SI, Sliman SM, Gurney TO, Loar B, Butler SO, Morris AJ, Marsh CB, Parinandi NL. Patel RB, et al. Among authors: kotha sr. Int J Toxicol. 2011 Feb;30(1):69-90. doi: 10.1177/1091581810388850. Epub 2010 Dec 3. Int J Toxicol. 2011. PMID: 21131602 Free PMC article.
52 results