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Hybrid molecules combining GABA-A and serotonin 5-HT6 receptors activity designed to tackle neuroinflammation associated with depression.
Marcinkowska M, Mordyl B, Fajkis-Zajaczkowska N, Siwek A, Karcz T, Gawalska A, Bucki A, Żmudzki P, Partyka A, Jastrzębska-Więsek M, Pomierny B, Walczak M, Smolik M, Pytka K, Mika K, Kotańska M, Kolaczkowski M. Marcinkowska M, et al. Among authors: kotanska m. Eur J Med Chem. 2023 Feb 5;247:115071. doi: 10.1016/j.ejmech.2022.115071. Epub 2022 Dec 29. Eur J Med Chem. 2023. PMID: 36603509
Chemically Homogenous Compounds with Antagonistic Properties at All α1-Adrenoceptor Subtypes but not β1-Adrenoceptor Attenuate Adrenaline-Induced Arrhythmia in Rats.
Pytka K, Lustyk K, Żmudzka E, Kotańska M, Siwek A, Zygmunt M, Dziedziczak A, Śniecikowska J, Olczyk A, Gałuszka A, Śmieja J, Waszkielewicz AM, Marona H, Filipek B, Sapa J, Mogilski S. Pytka K, et al. Among authors: kotanska m. Front Pharmacol. 2016 Aug 3;7:229. doi: 10.3389/fphar.2016.00229. eCollection 2016. Front Pharmacol. 2016. PMID: 27536240 Free PMC article.
Arylsulfonamide derivatives of (aryloxy)ethyl pyrrolidines and piperidines as α1-adrenergic receptor antagonist with uro-selective activity.
Rak A, Canale V, Marciniec K, Żmudzki P, Kotańska M, Knutelska J, Siwek A, Stachowicz G, Bednarski M, Nowiński L, Zygmunt M, Zajdel P, Sapa J. Rak A, et al. Among authors: kotanska m. Bioorg Med Chem. 2016 Nov 1;24(21):5582-5591. doi: 10.1016/j.bmc.2016.09.017. Epub 2016 Sep 10. Bioorg Med Chem. 2016. PMID: 27658792
61 results