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The 1,3,5-Triazine Derivatives as Innovative Chemical Family of 5-HT6 Serotonin Receptor Agents with Therapeutic Perspectives for Cognitive Impairment.
Latacz G, Lubelska A, Jastrzębska-Więsek M, Partyka A, Marć MA, Satała G, Wilczyńska D, Kotańska M, Więcek M, Kamińska K, Wesołowska A, Kieć-Kononowicz K, Handzlik J. Latacz G, et al. Among authors: kotanska m. Int J Mol Sci. 2019 Jul 12;20(14):3420. doi: 10.3390/ijms20143420. Int J Mol Sci. 2019. PMID: 31336820 Free PMC article.
Synthesis and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine derivatives as histamine H3R ligands.
Szczepańska K, Karcz T, Mogilski S, Siwek A, Kuder KJ, Latacz G, Kubacka M, Hagenow S, Lubelska A, Olejarz A, Kotańska M, Sadek B, Stark H, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: kotanska m. Eur J Med Chem. 2018 May 25;152:223-234. doi: 10.1016/j.ejmech.2018.04.043. Epub 2018 Apr 25. Eur J Med Chem. 2018. PMID: 29723785
Computer-Aided Studies for Novel Arylhydantoin 1,3,5-Triazine Derivatives as 5-HT₆ Serotonin Receptor Ligands with Antidepressive-Like, Anxiolytic and Antiobesity Action In Vivo.
Kurczab R, Ali W, Łażewska D, Kotańska M, Jastrzębska-Więsek M, Satała G, Więcek M, Lubelska A, Latacz G, Partyka A, Starek M, Dąbrowska M, Wesołowska A, Jacob C, Kieć-Kononowicz K, Handzlik J. Kurczab R, et al. Among authors: kotanska m. Molecules. 2018 Oct 3;23(10):2529. doi: 10.3390/molecules23102529. Molecules. 2018. PMID: 30282913 Free PMC article.
Optimization and preclinical evaluation of novel histamine H3receptor ligands: Acetyl and propionyl phenoxyalkyl piperazine derivatives.
Szczepańska K, Karcz T, Kotańska M, Siwek A, Kuder KJ, Latacz G, Mogilski S, Hagenow S, Lubelska A, Sobolewski M, Stark H, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: kotanska m. Bioorg Med Chem. 2018 Dec 15;26(23-24):6056-6066. doi: 10.1016/j.bmc.2018.11.010. Epub 2018 Nov 10. Bioorg Med Chem. 2018. PMID: 30448256
Anti-Alzheimer's multitarget-directed ligands with serotonin 5-HT6 antagonist, butyrylcholinesterase inhibitory, and antioxidant activity.
Marcinkowska M, Bucki A, Panek D, Siwek A, Fajkis N, Bednarski M, Zygmunt M, Godyń J, Del Rio Valdivieso A, Kotańska M, Kołaczkowski M, Więckowska A. Marcinkowska M, et al. Among authors: kotanska m. Arch Pharm (Weinheim). 2019 Jul;352(7):e1900041. doi: 10.1002/ardp.201900041. Epub 2019 Jun 4. Arch Pharm (Weinheim). 2019. PMID: 31162703
Structural modifications and in vitro pharmacological evaluation of 4-pyridyl-piperazine derivatives as an active and selective histamine H3 receptor ligands.
Szczepańska K, Karcz T, Siwek A, Kuder KJ, Latacz G, Bednarski M, Szafarz M, Hagenow S, Lubelska A, Olejarz-Maciej A, Sobolewski M, Mika K, Kotańska M, Stark H, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: kotanska m. Bioorg Chem. 2019 Oct;91:103071. doi: 10.1016/j.bioorg.2019.103071. Epub 2019 Jun 20. Bioorg Chem. 2019. PMID: 31362197
61 results