Koszła O - Search Results

1

Analysis of pharmacokinetic profile and ecotoxicological character of cefepime and its photodegradation products.

Żandarek J, Żmudzki P, Obradović D, Lazović S, Bogojević A, Koszła O, Sołek P, Maciąg M, Płazińska A, Starek M, Dąbrowska M. Żandarek J, et al. Among authors: koszla o. Chemosphere. 2024 Apr;353:141529. doi: 10.1016/j.chemosphere.2024.141529. Epub 2024 Feb 28. Chemosphere. 2024. PMID: 38428534

2

Synthesis of Novel 2-(Cyclopentylamino)thiazol-4(5H)-one Derivatives with Potential Anticancer, Antioxidant, and 11β-HSD Inhibitory Activities.

Baumgart S, Kupczyk D, Archała A, Koszła O, Sołek P, Płaziński W, Płazińska A, Studzińska R. Baumgart S, et al. Among authors: koszla o. Int J Mol Sci. 2023 Apr 14;24(8):7252. doi: 10.3390/ijms24087252. Int J Mol Sci. 2023. PMID: 37108415 Free PMC article.

3

Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes.

Bartuzi D, Kędzierska E, Targowska-Duda KM, Koszła O, Wróbel TM, Jademyr S, Karcz T, Szczepańska K, Stępnicki P, Wronikowska-Denysiuk O, Biała G, Handzlik J, Kristensen JL, Poso A, Kaczor AA. Bartuzi D, et al. Among authors: koszla o. Sci Rep. 2022 Dec 7;12(1):21192. doi: 10.1038/s41598-022-25478-7. Sci Rep. 2022. PMID: 36476619 Free PMC article.

4

Multitarget Derivatives of D2AAK1 as Potential Antipsychotics: The Effect of Substitution in the Indole Moiety.

Kondej M, Wróbel TM, Targowska-Duda KM, Leandro Martínez A, Koszła O, Stępnicki P, Zięba A, Paz A, Wronikowska-Denysiuk O, Loza MI, Castro M, Kaczor AA. Kondej M, et al. Among authors: koszla o. ChemMedChem. 2022 Aug 3;17(15):e202200238. doi: 10.1002/cmdc.202200238. Epub 2022 Jun 17. ChemMedChem. 2022. PMID: 35610178

5

Screening and Structure-Activity Relationship of D2AAK1 Derivatives for Potential Application in the Treatment of Neurodegenerative Diseases.

Koszła O, Sołek P, Stępnicki P, Kaczor AA. Koszła O, et al. Molecules. 2022 Mar 30;27(7):2239. doi: 10.3390/molecules27072239. Molecules. 2022. PMID: 35408637 Free PMC article.

6

In vitro and in vivo evaluation of antioxidant and neuroprotective properties of antipsychotic D2AAK1.

Koszła O, Sołek P, Kędzierska E, Listos P, Castro M, Kaczor AA. Koszła O, et al. Neurochem Res. 2022 Jun;47(6):1778-1789. doi: 10.1007/s11064-022-03570-8. Epub 2022 Apr 5. Neurochem Res. 2022. PMID: 35380398

7

Allosteric modulation of dopamine D_2L receptor in complex with G_i1 and G_i2 proteins: the effect of subtle structural and stereochemical ligand modifications.

Żuk J, Bartuzi D, Silva AG, Pitucha M, Koszła O, Wróbel TM, Matosiuk D, Castro M, Kaczor AA. Żuk J, et al. Among authors: koszla o. Pharmacol Rep. 2022 Apr;74(2):406-424. doi: 10.1007/s43440-021-00352-x. Epub 2022 Jan 22. Pharmacol Rep. 2022. PMID: 35064921 Free PMC article.

8

Cancer on-target: Selective enhancement of 3-bromopyruvate action by an electromagnetic field in vitro.

Sołek P, Mytych J, Łannik E, Majchrowicz L, Koszła O, Koziorowska A, Koziorowski M. Sołek P, et al. Among authors: koszla o. Free Radic Biol Med. 2022 Feb 20;180:153-164. doi: 10.1016/j.freeradbiomed.2022.01.011. Epub 2022 Jan 19. Free Radic Biol Med. 2022. PMID: 35063649

9

Current Approaches and Tools Used in Drug Development against Parkinson's Disease.

Koszła O, Stępnicki P, Zięba A, Grudzińska A, Matosiuk D, Kaczor AA. Koszła O, et al. Biomolecules. 2021 Jun 16;11(6):897. doi: 10.3390/biom11060897. Biomolecules. 2021. PMID: 34208760 Free PMC article. Review.

10

N-(3-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}propyl)-1H-indazole-3-carboxamide (D2AAK3) as a potential antipsychotic: In vitro, in silico and in vivo evaluation of a multi-target ligand.

Kaczor AA, Targowska-Duda KM, Stępnicki P, Silva AG, Koszła O, Kędzierska E, Grudzińska A, Kruk-Słomka M, Biała G, Castro M. Kaczor AA, et al. Among authors: koszla o. Neurochem Int. 2021 Jun;146:105016. doi: 10.1016/j.neuint.2021.105016. Epub 2021 Mar 17. Neurochem Int. 2021. PMID: 33722679

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