Kosyk O - Search Results

1

Acetaminophen-induced acute liver injury in HCV transgenic mice.

Uehara T, Kosyk O, Jeannot E, Bradford BU, Tech K, Macdonald JM, Boorman GA, Chatterjee S, Mason RP, Melnyk SB, Tryndyak VP, Pogribny IP, Rusyn I. Uehara T, et al. Among authors: kosyk o. Toxicol Appl Pharmacol. 2013 Jan 15;266(2):224-32. doi: 10.1016/j.taap.2012.11.019. Epub 2012 Nov 29. Toxicol Appl Pharmacol. 2013. PMID: 23200774 Free PMC article.

2

Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol-induced oxidative DNA damage in rodent liver.

Bradford BU, Kono H, Isayama F, Kosyk O, Wheeler MD, Akiyama TE, Bleye L, Krausz KW, Gonzalez FJ, Koop DR, Rusyn I. Bradford BU, et al. Among authors: kosyk o. Hepatology. 2005 Feb;41(2):336-44. doi: 10.1002/hep.20532. Hepatology. 2005. PMID: 15660387

3

Effects of ethylene oxide and ethylene inhalation on DNA adducts, apurinic/apyrimidinic sites and expression of base excision DNA repair genes in rat brain, spleen, and liver.

Rusyn I, Asakura S, Li Y, Kosyk O, Koc H, Nakamura J, Upton PB, Swenberg JA. Rusyn I, et al. Among authors: kosyk o. DNA Repair (Amst). 2005 Sep 28;4(10):1099-110. doi: 10.1016/j.dnarep.2005.05.009. DNA Repair (Amst). 2005. PMID: 16051529

4

Temporal correlation of pathology and DNA damage with gene expression in a choline-deficient model of rat liver injury.

Powell CL, Kosyk O, Bradford BU, Parker JS, Lobenhofer EK, Denda A, Uematsu F, Nakae D, Rusyn I. Powell CL, et al. Among authors: kosyk o. Hepatology. 2005 Nov;42(5):1137-47. doi: 10.1002/hep.20910. Hepatology. 2005. PMID: 16250055

5

Phenotypic anchoring of acetaminophen-induced oxidative stress with gene expression profiles in rat liver.

Powell CL, Kosyk O, Ross PK, Schoonhoven R, Boysen G, Swenberg JA, Heinloth AN, Boorman GA, Cunningham ML, Paules RS, Rusyn I. Powell CL, et al. Among authors: kosyk o. Toxicol Sci. 2006 Sep;93(1):213-22. doi: 10.1093/toxsci/kfl030. Epub 2006 Jun 2. Toxicol Sci. 2006. PMID: 16751229 Free PMC article.

6

WY-14,643 induced cell proliferation and oxidative stress in mouse liver are independent of NADPH oxidase.

Woods CG, Burns AM, Bradford BU, Ross PK, Kosyk O, Swenberg JA, Cunningham ML, Rusyn I. Woods CG, et al. Among authors: kosyk o. Toxicol Sci. 2007 Aug;98(2):366-74. doi: 10.1093/toxsci/kfm104. Epub 2007 May 5. Toxicol Sci. 2007. PMID: 17483499

7

Genome-level analysis of genetic regulation of liver gene expression networks.

Gatti D, Maki A, Chesler EJ, Kirova R, Kosyk O, Lu L, Manly KF, Williams RW, Perkins A, Langston MA, Threadgill DW, Rusyn I. Gatti D, et al. Among authors: kosyk o. Hepatology. 2007 Aug;46(2):548-57. doi: 10.1002/hep.21682. Hepatology. 2007. PMID: 17542012 Free PMC article.

8

Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses.

Beyer RP, Fry RC, Lasarev MR, McConnachie LA, Meira LB, Palmer VS, Powell CL, Ross PK, Bammler TK, Bradford BU, Cranson AB, Cunningham ML, Fannin RD, Higgins GM, Hurban P, Kayton RJ, Kerr KF, Kosyk O, Lobenhofer EK, Sieber SO, Vliet PA, Weis BK, Wolfinger R, Woods CG, Freedman JH, Linney E, Kaufmann WK, Kavanagh TJ, Paules RS, Rusyn I, Samson LD, Spencer PS, Suk W, Tennant RJ, Zarbl H; Members of the Toxicogenomics Research Consortium. Beyer RP, et al. Among authors: kosyk o. Toxicol Sci. 2007 Sep;99(1):326-37. doi: 10.1093/toxsci/kfm150. Epub 2007 Jun 11. Toxicol Sci. 2007. PMID: 17562736

9

Time course investigation of PPARalpha- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression.

Woods CG, Kosyk O, Bradford BU, Ross PK, Burns AM, Cunningham ML, Qu P, Ibrahim JG, Rusyn I. Woods CG, et al. Among authors: kosyk o. Toxicol Appl Pharmacol. 2007 Dec 15;225(3):267-77. doi: 10.1016/j.taap.2007.08.028. Epub 2007 Sep 16. Toxicol Appl Pharmacol. 2007. PMID: 17950772 Free PMC article.

10

Metabolomic profiling of a modified alcohol liquid diet model for liver injury in the mouse uncovers new markers of disease.

Bradford BU, O'Connell TM, Han J, Kosyk O, Shymonyak S, Ross PK, Winnike J, Kono H, Rusyn I. Bradford BU, et al. Among authors: kosyk o, o connell tm. Toxicol Appl Pharmacol. 2008 Oct 15;232(2):236-43. doi: 10.1016/j.taap.2008.06.022. Epub 2008 Jul 12. Toxicol Appl Pharmacol. 2008. PMID: 18674555 Free PMC article.

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