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Page 1
Epigenetic state determines inflammatory sensing in neuroblastoma.
Wolpaw AJ, Grossmann LD, Dessau JL, Dong MM, Aaron BJ, Brafford PA, Volgina D, Pascual-Pasto G, Rodriguez-Garcia A, Uzun Y, Arsenian-Henriksson M, Powell DJ Jr, Bosse KR, Kossenkov A, Tan K, Hogarty MD, Maris JM, Dang CV. Wolpaw AJ, et al. Among authors: kossenkov a. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2102358119. doi: 10.1073/pnas.2102358119. Proc Natl Acad Sci U S A. 2022. PMID: 35121657 Free PMC article.
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.
Caino MC, Ghosh JC, Chae YC, Vaira V, Rivadeneira DB, Faversani A, Rampini P, Kossenkov AV, Aird KM, Zhang R, Webster MR, Weeraratna AT, Bosari S, Languino LR, Altieri DC. Caino MC, et al. Among authors: kossenkov av. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8638-43. doi: 10.1073/pnas.1500722112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124089 Free PMC article.
Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance.
Liu J, Rebecca VW, Kossenkov AV, Connelly T, Liu Q, Gutierrez A, Xiao M, Li L, Zhang G, Samarkina A, Zayasbazan D, Zhang J, Cheng C, Wei Z, Alicea GM, Fukunaga-Kalabis M, Krepler C, Aza-Blanc P, Yang CC, Delvadia B, Tong C, Huang Y, Delvadia M, Morias AS, Sproesser K, Brafford P, Wang JX, Beqiri M, Somasundaram R, Vultur A, Hristova DM, Wu LW, Lu Y, Mills GB, Xu W, Karakousis GC, Xu X, Schuchter LM, Mitchell TC, Amaravadi RK, Kwong LN, Frederick DT, Boland GM, Salvino JM, Speicher DW, Flaherty KT, Ronai ZA, Herlyn M. Liu J, et al. Among authors: kossenkov av. Cancer Res. 2021 Oct 15;81(20):5230-5241. doi: 10.1158/0008-5472.CAN-20-1496. Epub 2021 Aug 30. Cancer Res. 2021. PMID: 34462276 Free PMC article.
Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability.
Ghosh JC, Perego M, Agarwal E, Bertolini I, Wang Y, Goldman AR, Tang HY, Kossenkov AV, Landis CJ, Languino LR, Plow EF, Morotti A, Ottobrini L, Locatelli M, Speicher DW, Caino MC, Cassel J, Salvino JM, Robert ME, Vaira V, Altieri DC. Ghosh JC, et al. Among authors: kossenkov av. Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2115624119. doi: 10.1073/pnas.2115624119. Proc Natl Acad Sci U S A. 2022. PMID: 35177476 Free PMC article.
The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer.
Mirji G, Worth A, Bhat SA, El Sayed M, Kannan T, Goldman AR, Tang HY, Liu Q, Auslander N, Dang CV, Abdel-Mohsen M, Kossenkov A, Stanger BZ, Shinde RS. Mirji G, et al. Among authors: kossenkov a. Sci Immunol. 2022 Sep 9;7(75):eabn0704. doi: 10.1126/sciimmunol.abn0704. Epub 2022 Sep 9. Sci Immunol. 2022. PMID: 36083892 Free PMC article.
Common activities and predictive gene signature identified for genetic hypomorphs of TP53.
Leung JC, Leu JI, Indeglia A, Kannan T, Clarke NL, Kirven NA, Dweep H, Garlick D, Barnoud T, Kossenkov AV, George DL, Murphy ME. Leung JC, et al. Among authors: kossenkov av. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2212940120. doi: 10.1073/pnas.2212940120. Epub 2023 Feb 7. Proc Natl Acad Sci U S A. 2023. PMID: 36749725 Free PMC article.
230 results