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Design and Synthesis of Novel 2-Acetamido, 6-Carboxamide Substituted Benzothiazoles as Potential BRAFV600E Inhibitors - In vitro Evaluation of their Antiproliferative Activity.
Batsi Y, Antonopoulou G, Fotopoulou T, Koumaki K, Kritsi E, Potamitis C, Goulielmaki M, Skarmalioraki S, Papalouka C, Poulou-Sidiropoulou E, Kosmidou V, Douna S, Vidali MS, Gkotsi EF, Chatziioannou A, Souliotis VL, Pletsa V, Papadodima O, Zoumpourlis V, Georgiadis P, Zervou M, Pintzas A, Kostas ID. Batsi Y, et al. Among authors: kosmidou v. ChemMedChem. 2023 Nov 16;18(22):e202300322. doi: 10.1002/cmdc.202300322. Epub 2023 Oct 24. ChemMedChem. 2023. PMID: 37792577
BRAF paradox breakers PLX8394, PLX7904 are more effective against BRAFV600Ε CRC cells compared with the BRAF inhibitor PLX4720 and shown by detailed pathway analysis.
Koumaki K, Kontogianni G, Kosmidou V, Pahitsa F, Kritsi E, Zervou M, Chatziioannou A, Souliotis VL, Papadodima O, Pintzas A. Koumaki K, et al. Among authors: kosmidou v. Biochim Biophys Acta Mol Basis Dis. 2021 Apr 1;1867(4):166061. doi: 10.1016/j.bbadis.2020.166061. Epub 2020 Dec 29. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33385518 Free article.
Noxa upregulation and 5-gene apoptotic biomarker panel in colorectal cancer.
Kosmidou V, Vlassi M, Anagiotos K, Raftopoulou S, Kalogerakou E, Skarmalioraki S, Aggeli C, Choreftaki T, Zografos G, Pintzas A. Kosmidou V, et al. Eur J Clin Invest. 2021 Jan;51(1):e13353. doi: 10.1111/eci.13353. Epub 2020 Aug 11. Eur J Clin Invest. 2021. PMID: 32682341
Epigenetic regulation of miR-21 in colorectal cancer: ITGB4 as a novel miR-21 target and a three-gene network (miR-21-ITGΒ4-PDCD4) as predictor of metastatic tumor potential.
Ferraro A, Kontos CK, Boni T, Bantounas I, Siakouli D, Kosmidou V, Vlassi M, Spyridakis Y, Tsipras I, Zografos G, Pintzas A. Ferraro A, et al. Among authors: kosmidou v. Epigenetics. 2014 Jan;9(1):129-41. doi: 10.4161/epi.26842. Epub 2013 Oct 22. Epigenetics. 2014. PMID: 24149370 Free PMC article.
28 results