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Neuron-astrocyte transmitophagy is altered in Alzheimer's disease.
Lampinen R, Belaya I, Saveleva L, Liddell JR, Rait D, Huuskonen MT, Giniatullina R, Sorvari A, Soppela L, Mikhailov N, Boccuni I, Giniatullin R, Cruz-Haces M, Konovalova J, Koskuvi M, Domanskyi A, Hämäläinen RH, Goldsteins G, Koistinaho J, Malm T, Chew S, Rilla K, White AR, Marsh-Armstrong N, Kanninen KM. Lampinen R, et al. Among authors: koskuvi m. Neurobiol Dis. 2022 Aug;170:105753. doi: 10.1016/j.nbd.2022.105753. Epub 2022 May 13. Neurobiol Dis. 2022. PMID: 35569719 Free article.
NF-E2-related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin-1 mutated Alzheimer's disease astrocytes.
Oksanen M, Hyötyläinen I, Trontti K, Rolova T, Wojciechowski S, Koskuvi M, Viitanen M, Levonen AL, Hovatta I, Roybon L, Lehtonen Š, Kanninen KM, Hämäläinen RH, Koistinaho J. Oksanen M, et al. Among authors: koskuvi m. Glia. 2020 Mar;68(3):589-599. doi: 10.1002/glia.23741. Epub 2019 Oct 31. Glia. 2020. PMID: 31670864 Free PMC article.
Metabolic alterations in Parkinson's disease astrocytes.
Sonninen TM, Hämäläinen RH, Koskuvi M, Oksanen M, Shakirzyanova A, Wojciechowski S, Puttonen K, Naumenko N, Goldsteins G, Laham-Karam N, Lehtonen M, Tavi P, Koistinaho J, Lehtonen Š. Sonninen TM, et al. Among authors: koskuvi m. Sci Rep. 2020 Sep 2;10(1):14474. doi: 10.1038/s41598-020-71329-8. Sci Rep. 2020. PMID: 32879386 Free PMC article.
Generation of a human induced pluripotent stem cell line (UEFi003-A) carrying heterozygous A673T variant in amyloid precursor protein associated with a reduced risk of Alzheimer's disease.
Rolova T, Wu YC, Koskuvi M, Voutilainen J, Sonninen TM, Kuusisto J, Laakso M, Hämäläinen RH, Koistinaho J, Lehtonen Š. Rolova T, et al. Among authors: koskuvi m. Stem Cell Res. 2020 Oct;48:101968. doi: 10.1016/j.scr.2020.101968. Epub 2020 Sep 2. Stem Cell Res. 2020. PMID: 32911327 Free article.
Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia.
Koskuvi M, Lehtonen Š, Trontti K, Keuters M, Wu YC, Koivisto H, Ludwig A, Plotnikova L, Virtanen PLJ, Räsänen N, Kaipainen S, Hyötyläinen I, Dhungana H, Giniatullina R, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Lähteenvuo M, Tohka J, Giniatullin R, Rivera C, Hovatta I, Tanila H, Tiihonen J, Koistinaho J. Koskuvi M, et al. Glia. 2022 Apr;70(4):650-660. doi: 10.1002/glia.24131. Epub 2021 Dec 22. Glia. 2022. PMID: 34936134 Free PMC article.
Sex-specific transcriptional and proteomic signatures in schizophrenia.
Tiihonen J, Koskuvi M, Storvik M, Hyötyläinen I, Gao Y, Puttonen KA, Giniatullina R, Poguzhelskaya E, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Cheng L, Hill AF, Lähteenvuo M, Tohka J, Giniatullin R, Lehtonen Š, Koistinaho J. Tiihonen J, et al. Among authors: koskuvi m. Nat Commun. 2019 Sep 2;10(1):3933. doi: 10.1038/s41467-019-11797-3. Nat Commun. 2019. PMID: 31477693 Free PMC article.
Microglia-like Cells Promote Neuronal Functions in Cerebral Organoids.
Fagerlund I, Dougalis A, Shakirzyanova A, Gómez-Budia M, Pelkonen A, Konttinen H, Ohtonen S, Fazaludeen MF, Koskuvi M, Kuusisto J, Hernández D, Pebay A, Koistinaho J, Rauramaa T, Lehtonen Š, Korhonen P, Malm T. Fagerlund I, et al. Among authors: koskuvi m. Cells. 2021 Dec 30;11(1):124. doi: 10.3390/cells11010124. Cells. 2021. PMID: 35011686 Free PMC article.
The iPSC perspective on schizophrenia.
Räsänen N, Tiihonen J, Koskuvi M, Lehtonen Š, Koistinaho J. Räsänen N, et al. Among authors: koskuvi m. Trends Neurosci. 2022 Jan;45(1):8-26. doi: 10.1016/j.tins.2021.11.002. Epub 2021 Dec 4. Trends Neurosci. 2022. PMID: 34876311 Free article. Review.
Molecular signaling pathways underlying schizophrenia.
Tiihonen J, Koskuvi M, Lähteenvuo M, Trontti K, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Cheng L, Tanskanen A, Taipale H, Lehtonen Š, Koistinaho J. Tiihonen J, et al. Among authors: koskuvi m. Schizophr Res. 2021 Jun;232:33-41. doi: 10.1016/j.schres.2021.05.011. Epub 2021 May 16. Schizophr Res. 2021. PMID: 34010744 Free article.
17 results