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Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection.
Lamarthée B, Callemeyn J, Van Herck Y, Antoranz A, Anglicheau D, Boada P, Becker JU, Debyser T, De Smet F, De Vusser K, Eloudzeri M, Franken A, Gwinner W, Koshy P, Kuypers D, Lambrechts D, Marquet P, Mathias V, Rabant M, Sarwal MM, Senev A, Sigdel TK, Sprangers B, Thaunat O, Tinel C, Van Brussel T, Van Craenenbroeck A, Van Loon E, Vaulet T, Bosisio F, Naesens M. Lamarthée B, et al. Among authors: koshy p. Nat Commun. 2023 Jul 19;14(1):4359. doi: 10.1038/s41467-023-39859-7. Nat Commun. 2023. PMID: 37468466 Free PMC article.
Allorecognition and the spectrum of kidney transplant rejection.
Callemeyn J, Lamarthée B, Koenig A, Koshy P, Thaunat O, Naesens M. Callemeyn J, et al. Among authors: koshy p. Kidney Int. 2022 Apr;101(4):692-710. doi: 10.1016/j.kint.2021.11.029. Epub 2021 Dec 13. Kidney Int. 2022. PMID: 34915041 Free article. Review.
Circulating Donor-Specific Anti-HLA Antibodies Associate With Immune Activation Independent of Kidney Transplant Histopathological Findings.
Van Loon E, Lamarthée B, Barba T, Claes S, Coemans M, de Loor H, Emonds MP, Koshy P, Kuypers D, Proost P, Senev A, Sprangers B, Tinel C, Thaunat O, Van Craenenbroeck AH, Schols D, Naesens M. Van Loon E, et al. Among authors: koshy p. Front Immunol. 2022 Feb 23;13:818569. doi: 10.3389/fimmu.2022.818569. eCollection 2022. Front Immunol. 2022. PMID: 35281018 Free PMC article.
Biological pathways and comparison with biopsy signals and cellular origin of peripheral blood transcriptomic profiles during kidney allograft pathology.
Van Loon E, Lamarthée B, de Loor H, Van Craenenbroeck AH, Brouard S, Danger R, Giral M, Callemeyn J, Tinel C, Cortés Calabuig Á, Koshy P, Sprangers B, Kuypers D, Gwinner W, Anglicheau D, Marquet P, Naesens M. Van Loon E, et al. Among authors: koshy p. Kidney Int. 2022 Jul;102(1):183-195. doi: 10.1016/j.kint.2022.03.026. Epub 2022 May 5. Kidney Int. 2022. PMID: 35526671 Free PMC article.
Association of HLA Mismatches and Histology Suggestive of Antibody-Mediated Injury in the Absence of Donor-Specific Anti-HLA Antibodies.
Senev A, Lerut E, Coemans M, Callemeyn J, Copley HC, Claas F, Koshy P, Kosmoliaptsis V, Kuypers D, Sprangers B, Van Craenenbroeck A, Van Loon E, Van Sandt V, Emonds MP, Naesens M. Senev A, et al. Among authors: koshy p. Clin J Am Soc Nephrol. 2022 Aug;17(8):1204-1215. doi: 10.2215/CJN.00570122. Epub 2022 Jun 1. Clin J Am Soc Nephrol. 2022. PMID: 35649719 Free PMC article.
Association of Predicted HLA T-Cell Epitope Targets and T-Cell-Mediated Rejection After Kidney Transplantation.
Senev A, Van Loon E, Lerut E, Coemans M, Callemeyn J, Daniëls L, Kerkhofs J, Koshy P, Kuypers D, Lamarthée B, Sprangers B, Tinel C, Van Craenenbroeck AH, Van Sandt V, Emonds MP, Naesens M. Senev A, et al. Among authors: koshy p. Am J Kidney Dis. 2022 Dec;80(6):718-729.e1. doi: 10.1053/j.ajkd.2022.04.009. Epub 2022 Jun 9. Am J Kidney Dis. 2022. PMID: 35690154
Data-Driven Chronic Allograft Phenotypes: A Novel and Validated Complement for Histologic Assessment of Kidney Transplant Biopsies.
Vaulet T, Divard G, Thaunat O, Koshy P, Lerut E, Senev A, Aubert O, Van Loon E, Callemeyn J, Emonds MP, Van Craenenbroeck A, De Vusser K, Sprangers B, Rabeyrin M, Dubois V, Kuypers D, De Vos M, Loupy A, De Moor B, Naesens M. Vaulet T, et al. Among authors: koshy p. J Am Soc Nephrol. 2022 Nov;33(11):2026-2039. doi: 10.1681/ASN.2022030290. Epub 2022 Sep 7. J Am Soc Nephrol. 2022. PMID: 36316096 Free PMC article.
Epidemiology, Outcomes, and Complement Gene Variants in Secondary Thrombotic Microangiopathies.
Werion A, Storms P, Zizi Y, Beguin C, Bernards J, Cambier JF, Dahan K, Dierickx D, Godefroid N, Hilbert P, Lambert C, Levtchenko E, Meyskens T, Poiré X, van den Heuvel L, Claes KJ, Morelle J; UCLouvain TMA/HUS Network and KU Leuven TMA/HUS Network. Werion A, et al. Clin J Am Soc Nephrol. 2023 Apr 21;18(7):881-91. doi: 10.2215/CJN.0000000000000182. Online ahead of print. Clin J Am Soc Nephrol. 2023. PMID: 37094330
139 results