Kosciuk T - Search Results

1

A STAT3 palmitoylation cycle promotes T_H17 differentiation and colitis.

Zhang M, Zhou L, Xu Y, Yang M, Xu Y, Komaniecki GP, Kosciuk T, Chen X, Lu X, Zou X, Linder ME, Lin H. Zhang M, et al. Among authors: kosciuk t. Nature. 2020 Oct;586(7829):434-439. doi: 10.1038/s41586-020-2799-2. Epub 2020 Oct 7. Nature. 2020. PMID: 33029007 Free PMC article.

2

NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle.

Kosciuk T, Price IR, Zhang X, Zhu C, Johnson KN, Zhang S, Halaby SL, Komaniecki GP, Yang M, DeHart CJ, Thomas PM, Kelleher NL, Fromme JC, Lin H. Kosciuk T, et al. Nat Commun. 2020 Feb 26;11(1):1067. doi: 10.1038/s41467-020-14893-x. Nat Commun. 2020. PMID: 32103017 Free PMC article.

3

N-Myristoyltransferase as a Glycine and Lysine Myristoyltransferase in Cancer, Immunity, and Infections.

Kosciuk T, Lin H. Kosciuk T, et al. ACS Chem Biol. 2020 Jul 17;15(7):1747-1758. doi: 10.1021/acschembio.0c00314. Epub 2020 Jun 10. ACS Chem Biol. 2020. PMID: 32453941 Free PMC article. Review.

4

Updates on the epigenetic roles of sirtuins.

Kosciuk T, Wang M, Hong JY, Lin H. Kosciuk T, et al. Curr Opin Chem Biol. 2019 Aug;51:18-29. doi: 10.1016/j.cbpa.2019.01.023. Epub 2019 Mar 12. Curr Opin Chem Biol. 2019. PMID: 30875552 Free PMC article. Review.

5

Binding Affinity Determines Substrate Specificity and Enables Discovery of Substrates for N-Myristoyltransferases.

Su D, Kosciuk T, Yang M, Price IR, Lin H. Su D, et al. Among authors: kosciuk t. ACS Catal. 2021 Dec 17;11(24):14877-14883. doi: 10.1021/acscatal.1c03330. Epub 2021 Nov 29. ACS Catal. 2021. PMID: 34956690 Free PMC article.

6

Reply to Comment on "Binding Affinity Determines Substrate Specificity and Enables Discovery of substrates for N-Myristoyltransferases".

Su D, Kosciuk T, Lin H. Su D, et al. Among authors: kosciuk t. ACS Catal. 2022 Aug 5;12(15):8829-8832. doi: 10.1021/acscatal.2c01818. Epub 2022 Jul 8. ACS Catal. 2022. PMID: 35966602 Free PMC article.

7

Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model.

Farooqi AS, Hong JY, Cao J, Lu X, Price IR, Zhao Q, Kosciuk T, Yang M, Bai JJ, Lin H. Farooqi AS, et al. Among authors: kosciuk t. J Med Chem. 2019 Apr 25;62(8):4131-4141. doi: 10.1021/acs.jmedchem.9b00191. Epub 2019 Apr 15. J Med Chem. 2019. PMID: 30986062 Free PMC article.

8

Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression.

Oudin MJ, Jonas O, Kosciuk T, Broye LC, Guido BC, Wyckoff J, Riquelme D, Lamar JM, Asokan SB, Whittaker C, Ma D, Langer R, Cima MJ, Wisinski KB, Hynes RO, Lauffenburger DA, Keely PJ, Bear JE, Gertler FB. Oudin MJ, et al. Among authors: kosciuk t. Cancer Discov. 2016 May;6(5):516-31. doi: 10.1158/2159-8290.CD-15-1183. Epub 2016 Jan 25. Cancer Discov. 2016. PMID: 26811325 Free PMC article.

9

MENA Confers Resistance to Paclitaxel in Triple-Negative Breast Cancer.

Oudin MJ, Barbier L, Schäfer C, Kosciuk T, Miller MA, Han S, Jonas O, Lauffenburger DA, Gertler FB. Oudin MJ, et al. Among authors: kosciuk t. Mol Cancer Ther. 2017 Jan;16(1):143-155. doi: 10.1158/1535-7163.MCT-16-0413. Epub 2016 Nov 3. Mol Cancer Ther. 2017. PMID: 27811011 Free PMC article.

10

MenaINV mediates synergistic cross-talk between signaling pathways driving chemotaxis and haptotaxis.

Oudin MJ, Miller MA, Klazen JA, Kosciuk T, Lussiez A, Hughes SK, Tadros J, Bear JE, Lauffenburger DA, Gertler FB. Oudin MJ, et al. Among authors: kosciuk t. Mol Biol Cell. 2016 Oct 15;27(20):3085-3094. doi: 10.1091/mbc.E16-04-0212. Epub 2016 Aug 24. Mol Biol Cell. 2016. PMID: 27559126 Free PMC article.

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