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PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma.
Duchatel RJ, Jackson ER, Parackal SG, Kiltschewskij D, Findlay IJ, Mannan A, Staudt DE, Thomas BC, Germon ZP, Laternser S, Kearney PS, Jamaluddin MFB, Douglas AM, Beitaki T, McEwen HP, Persson ML, Hocke EA, Jain V, Aksu M, Manning EE, Murray HC, Verrills NM, Sun CX, Daniel P, Vilain RE, Skerrett-Byrne DA, Nixon B, Hua S, de Bock CE, Colino-Sanguino Y, Valdes-Mora F, Tsoli M, Ziegler DS, Cairns MJ, Raabe EH, Vitanza NA, Hulleman E, Phoenix TN, Koschmann C, Alvaro F, Dayas CV, Tinkle CL, Wheeler H, Whittle JR, Eisenstat DD, Firestein R, Mueller S, Valvi S, Hansford JR, Ashley DM, Gregory SG, Kilburn LB, Nazarian J, Cain JE, Dun MD. Duchatel RJ, et al. Among authors: koschmann c. J Clin Invest. 2024 Feb 6;134(6):e170329. doi: 10.1172/JCI170329. J Clin Invest. 2024. PMID: 38319732 Free PMC article.
CSF H3F3A K27M circulating tumor DNA copy number quantifies tumor growth and in vitro treatment response.
Stallard S, Savelieff MG, Wierzbicki K, Mullan B, Miklja Z, Bruzek A, Garcia T, Siada R, Anderson B, Singer BH, Hashizume R, Carcaboso AM, McMurray KQ, Heth J, Muraszko K, Robertson PL, Mody R, Venneti S, Garton H, Koschmann C. Stallard S, et al. Among authors: koschmann c. Acta Neuropathol Commun. 2018 Aug 15;6(1):80. doi: 10.1186/s40478-018-0580-7. Acta Neuropathol Commun. 2018. PMID: 30111355 Free PMC article. No abstract available.
Seq-ing the SINEs of central nervous system tumors in cerebrospinal fluid.
Douville C, Curtis S, Summers M, Azad TD, Rincon-Torroella J, Wang Y, Mattox A, Avigdor B, Dudley J, Materi J, Raj D, Nair S, Bhanja D, Tuohy K, Dobbyn L, Popoli M, Ptak J, Nehme N, Silliman N, Blair C, Judge K, Gallia GL, Groves M, Jackson CM, Jackson EM, Laterra J, Lim M, Mukherjee D, Weingart J, Naidoo J, Koschmann C, Smith N, Schreck KC, Pardo CA, Glantz M, Holdhoff M, Kinzler KW, Papadopoulos N, Vogelstein B, Bettegowda C. Douville C, et al. Among authors: koschmann c. Cell Rep Med. 2023 Aug 15;4(8):101148. doi: 10.1016/j.xcrm.2023.101148. Epub 2023 Aug 7. Cell Rep Med. 2023. PMID: 37552989 Free PMC article.
Recent advances and future of immunotherapy for glioblastoma.
Kamran N, Calinescu A, Candolfi M, Chandran M, Mineharu Y, Asad AS, Koschmann C, Nunez FJ, Lowenstein PR, Castro MG. Kamran N, et al. Among authors: koschmann c. Expert Opin Biol Ther. 2016 Oct;16(10):1245-64. doi: 10.1080/14712598.2016.1212012. Epub 2016 Jul 27. Expert Opin Biol Ther. 2016. PMID: 27411023 Free PMC article. Review.
The Emerging Role of Ras Pathway Signaling in Pediatric Cancer.
Ney GM, McKay L, Koschmann C, Mody R, Li Q. Ney GM, et al. Among authors: koschmann c. Cancer Res. 2020 Dec 1;80(23):5155-5163. doi: 10.1158/0008-5472.CAN-20-0916. Epub 2020 Sep 9. Cancer Res. 2020. PMID: 32907837 Free PMC article. Review.
Integrating RNA sequencing into neuro-oncology practice.
Rogawski DS, Vitanza NA, Gauthier AC, Ramaswamy V, Koschmann C. Rogawski DS, et al. Among authors: koschmann c. Transl Res. 2017 Nov;189:93-104. doi: 10.1016/j.trsl.2017.06.013. Epub 2017 Jul 8. Transl Res. 2017. PMID: 28746860 Free PMC article. Review.
Everolimus improves the efficacy of dasatinib in PDGFRα-driven glioma.
Miklja Z, Yadav VN, Cartaxo RT, Siada R, Thomas CC, Cummings JR, Mullan B, Stallard S, Paul A, Bruzek AK, Wierzbicki K, Yang T, Garcia T, Wolfe I, Leonard M, Robertson PL, Garton HJ, Wahl DR, Parmar H, Sarkaria JN, Kline C, Mueller S, Nicolaides T, Glasser C, Leary SE, Venneti S, Kumar-Sinha C, Chinnaiyan AM, Mody R, Pai MP, Phoenix TN, Marini BL, Koschmann C. Miklja Z, et al. Among authors: koschmann c. J Clin Invest. 2020 Oct 1;130(10):5313-5325. doi: 10.1172/JCI133310. J Clin Invest. 2020. PMID: 32603316 Free PMC article.
Characteristics of patients ≥10 years of age with diffuse intrinsic pontine glioma: a report from the International DIPG/DMG Registry.
Erker C, Lane A, Chaney B, Leary S, Minturn JE, Bartels U, Packer RJ, Dorris K, Gottardo NG, Warren KE, Broniscer A, Kieran MW, Zhu X, White P, Dexheimer PJ, Black K, Asher A, DeWire M, Hansford JR, Gururangan S, Nazarian J, Ziegler DS, Sandler E, Bartlett A, Goldman S, Shih CS, Hassall T, Dholaria H, Bandopadhayay P, Samson Y, Monje M, Fisher PG, Dodgshun A, Parkin S, Chintagumpala M, Tsui K, Gass D, Larouche V, Broxson E, Garcia Lombardi M, Wang SS, Ma J, Hawkins C, Hamideh D, Wagner L, Koschmann C, Fuller C, Drissi R, Jones BV, Leach J, Fouladi M. Erker C, et al. Among authors: koschmann c. Neuro Oncol. 2022 Jan 5;24(1):141-152. doi: 10.1093/neuonc/noab140. Neuro Oncol. 2022. PMID: 34114629 Free PMC article.
97 results