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PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling.
Thürmer M, Gollowitzer A, Pein H, Neukirch K, Gelmez E, Waltl L, Wielsch N, Winkler R, Löser K, Grander J, Hotze M, Harder S, Döding A, Meßner M, Troisi F, Ardelt M, Schlüter H, Pachmayr J, Gutiérrez-Gutiérrez Ó, Rudolph KL, Thedieck K, Schulze-Späte U, González-Estévez C, Kosan C, Svatoš A, Kwiatkowski M, Koeberle A. Thürmer M, et al. Among authors: kosan c. Nat Commun. 2022 May 27;13(1):2982. doi: 10.1038/s41467-022-30374-9. Nat Commun. 2022. PMID: 35624087 Free PMC article.
Effects of HDACi on Immunological Functions.
Winkler R, Kosan C. Winkler R, et al. Among authors: kosan c. Methods Mol Biol. 2017;1510:93-101. doi: 10.1007/978-1-4939-6527-4_7. Methods Mol Biol. 2017. PMID: 27761815
Tuberous sclerosis complex is required for tumor maintenance in MYC-driven Burkitt's lymphoma.
Hartleben G, Müller C, Krämer A, Schimmel H, Zidek LM, Dornblut C, Winkler R, Eichwald S, Kortman G, Kosan C, Kluiver J, Petersen I, van den Berg A, Wang ZQ, Calkhoven CF. Hartleben G, et al. Among authors: kosan c. EMBO J. 2018 Nov 2;37(21):e98589. doi: 10.15252/embj.201798589. Epub 2018 Sep 20. EMBO J. 2018. PMID: 30237309 Free PMC article.
Endoplasmic reticulum stress and the unfolded protein response in skeletal muscle of subjects suffering from peritoneal sepsis.
Metzing UB, von Loeffelholz C, Steidl R, Romeike B, Winkler R, Rauchfuß F, Settmacher U, Stoppe C, Coldewey SM, Weinmann C, Weickert MO, Claus RA, Birkenfeld AL, Kosan C, Horn P. Metzing UB, et al. Among authors: kosan c. Sci Rep. 2022 Jan 11;12(1):504. doi: 10.1038/s41598-021-04517-9. Sci Rep. 2022. PMID: 35017615 Free PMC article.
Sepsis-Induced Thymic Atrophy Is Associated with Defects in Early Lymphopoiesis.
Kong Y, Li Y, Zhang W, Yuan S, Winkler R, Kröhnert U, Han J, Lin T, Zhou Y, Miao P, Wang B, Zhang J, Yu Z, Zhang Y, Kosan C, Zeng H. Kong Y, et al. Among authors: kosan c. Stem Cells. 2016 Dec;34(12):2902-2915. doi: 10.1002/stem.2464. Epub 2016 Aug 1. Stem Cells. 2016. PMID: 27422171
Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition.
Winkler R, Mägdefrau AS, Piskor EM, Kleemann M, Beyer M, Linke K, Hansen L, Schaffer AM, Hoffmann ME, Poepsel S, Heyd F, Beli P, Möröy T, Mahboobi S, Krämer OH, Kosan C. Winkler R, et al. Among authors: kosan c. Oncogene. 2022 Sep;41(40):4560-4572. doi: 10.1038/s41388-022-02450-3. Epub 2022 Sep 6. Oncogene. 2022. PMID: 36068335 Free PMC article.
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