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Druggable growth dependencies and tumor evolution analysis in patient-derived organoids of neuroendocrine neoplasms from multiple body sites.
Dayton TL, Alcala N, Moonen L, den Hartigh L, Geurts V, Mangiante L, Lap L, Dost AFM, Beumer J, Levy S, van Leeuwaarde RS, Hackeng WM, Samsom K, Voegele C, Sexton-Oates A, Begthel H, Korving J, Hillen L, Brosens LAA, Lantuejoul S, Jaksani S, Kok NFM, Hartemink KJ, Klomp HM, Borel Rinkes IHM, Dingemans AM, Valk GD, Vriens MR, Buikhuisen W, van den Berg J, Tesselaar M, Derks J, Speel EJ, Foll M, Fernández-Cuesta L, Clevers H. Dayton TL, et al. Among authors: korving j. Cancer Cell. 2023 Dec 11;41(12):2083-2099.e9. doi: 10.1016/j.ccell.2023.11.007. Cancer Cell. 2023. PMID: 38086335 Free article.
The Wnt/beta-catenin pathway regulates cardiac valve formation.
Hurlstone AF, Haramis AP, Wienholds E, Begthel H, Korving J, Van Eeden F, Cuppen E, Zivkovic D, Plasterk RH, Clevers H. Hurlstone AF, et al. Among authors: korving j. Nature. 2003 Oct 9;425(6958):633-7. doi: 10.1038/nature02028. Nature. 2003. PMID: 14534590 Free article.
Identification of stem cells in small intestine and colon by marker gene Lgr5.
Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H. Barker N, et al. Among authors: korving j. Nature. 2007 Oct 25;449(7165):1003-7. doi: 10.1038/nature06196. Epub 2007 Oct 14. Nature. 2007. PMID: 17934449
Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro.
Barker N, Huch M, Kujala P, van de Wetering M, Snippert HJ, van Es JH, Sato T, Stange DE, Begthel H, van den Born M, Danenberg E, van den Brink S, Korving J, Abo A, Peters PJ, Wright N, Poulsom R, Clevers H. Barker N, et al. Among authors: korving j. Cell Stem Cell. 2010 Jan 8;6(1):25-36. doi: 10.1016/j.stem.2009.11.013. Cell Stem Cell. 2010. PMID: 20085740 Free article.
Sequential cancer mutations in cultured human intestinal stem cells.
Drost J, van Jaarsveld RH, Ponsioen B, Zimberlin C, van Boxtel R, Buijs A, Sachs N, Overmeer RM, Offerhaus GJ, Begthel H, Korving J, van de Wetering M, Schwank G, Logtenberg M, Cuppen E, Snippert HJ, Medema JP, Kops GJ, Clevers H. Drost J, et al. Among authors: korving j. Nature. 2015 May 7;521(7550):43-7. doi: 10.1038/nature14415. Epub 2015 Apr 29. Nature. 2015. PMID: 25924068
69 results