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Page 1
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Abbosh C, Frankell AM, Harrison T, Kisistok J, Garnett A, Johnson L, Veeriah S, Moreau M, Chesh A, Chaunzwa TL, Weiss J, Schroeder MR, Ward S, Grigoriadis K, Shahpurwalla A, Litchfield K, Puttick C, Biswas D, Karasaki T, Black JRM, Martínez-Ruiz C, Bakir MA, Pich O, Watkins TBK, Lim EL, Huebner A, Moore DA, Godin-Heymann N, L'Hernault A, Bye H, Odell A, Roberts P, Gomes F, Patel AJ, Manzano E, Hiley CT, Carey N, Riley J, Cook DE, Hodgson D, Stetson D, Barrett JC, Kortlever RM, Evan GI, Hackshaw A, Daber RD, Shaw JA, Aerts HJWL, Licon A, Stahl J, Jamal-Hanjani M; TRACERx Consortium; Birkbak NJ, McGranahan N, Swanton C. Abbosh C, et al. Among authors: kortlever rm. Nature. 2023 Apr;616(7957):553-562. doi: 10.1038/s41586-023-05776-4. Epub 2023 Apr 13. Nature. 2023. PMID: 37055640 Free PMC article.
Reversible Myc hypomorphism identifies a key Myc-dependency in early cancer evolution.
Sodir NM, Pellegrinet L, Kortlever RM, Campos T, Kwon YW, Kim S, Garcia D, Perfetto A, Anastasiou P, Swigart LB, Arends MJ, Littlewood TD, Evan GI. Sodir NM, et al. Among authors: kortlever rm. Nat Commun. 2022 Nov 9;13(1):6782. doi: 10.1038/s41467-022-34079-x. Nat Commun. 2022. PMID: 36351945 Free PMC article.
Selective activation of p53-mediated tumour suppression in high-grade tumours.
Junttila MR, Karnezis AN, Garcia D, Madriles F, Kortlever RM, Rostker F, Brown Swigart L, Pham DM, Seo Y, Evan GI, Martins CP. Junttila MR, et al. Among authors: kortlever rm. Nature. 2010 Nov 25;468(7323):567-71. doi: 10.1038/nature09526. Nature. 2010. PMID: 21107427 Free PMC article.
Heterogeneity of Myc expression in breast cancer exposes pharmacological vulnerabilities revealed through executable mechanistic modeling.
Kreuzaler P, Clarke MA, Brown EJ, Wilson CH, Kortlever RM, Piterman N, Littlewood T, Evan GI, Fisher J. Kreuzaler P, et al. Among authors: kortlever rm. Proc Natl Acad Sci U S A. 2019 Oct 29;116(44):22399-22408. doi: 10.1073/pnas.1903485116. Epub 2019 Oct 14. Proc Natl Acad Sci U S A. 2019. PMID: 31611367 Free PMC article.
MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype.
Sodir NM, Kortlever RM, Barthet VJA, Campos T, Pellegrinet L, Kupczak S, Anastasiou P, Swigart LB, Soucek L, Arends MJ, Littlewood TD, Evan GI. Sodir NM, et al. Among authors: kortlever rm. Cancer Discov. 2020 Apr;10(4):588-607. doi: 10.1158/2159-8290.CD-19-0435. Epub 2020 Jan 15. Cancer Discov. 2020. PMID: 31941709
14 results