Kortholt A - Search Results

1

Connecting G protein signaling to chemoattractant-mediated cell polarity and cytoskeletal reorganization.

Liu Y, Lacal J, Firtel RA, Kortholt A. Liu Y, et al. Among authors: kortholt a. Small GTPases. 2018 Jul 4;9(4):360-364. doi: 10.1080/21541248.2016.1235390. Epub 2016 Oct 14. Small GTPases. 2018. PMID: 27715492 Free PMC article. Review.

2

Characterization of the GbpD-activated Rap1 pathway regulating adhesion and cell polarity in Dictyostelium discoideum.

Kortholt A, Rehmann H, Kae H, Bosgraaf L, Keizer-Gunnink I, Weeks G, Wittinghofer A, Van Haastert PJ. Kortholt A, et al. J Biol Chem. 2006 Aug 18;281(33):23367-76. doi: 10.1074/jbc.M600804200. Epub 2006 Jun 12. J Biol Chem. 2006. PMID: 16769729 Free article.

3

Chemoattractants and chemorepellents act by inducing opposite polarity in phospholipase C and PI3-kinase signaling.

Keizer-Gunnink I, Kortholt A, Van Haastert PJ. Keizer-Gunnink I, et al. Among authors: kortholt a. J Cell Biol. 2007 May 21;177(4):579-85. doi: 10.1083/jcb.200611046. J Cell Biol. 2007. PMID: 17517960 Free PMC article.

4

Highlighting the role of Ras and Rap during Dictyostelium chemotaxis.

Kortholt A, van Haastert PJ. Kortholt A, et al. Cell Signal. 2008 Aug;20(8):1415-22. doi: 10.1016/j.cellsig.2008.02.006. Epub 2008 Apr 1. Cell Signal. 2008. PMID: 18385017 Free article. Review.

5

Daydreamer, a Ras effector and GSK-3 substrate, is important for directional sensing and cell motility.

Kölsch V, Shen Z, Lee S, Plak K, Lotfi P, Chang J, Charest PG, Romero JL, Jeon TJ, Kortholt A, Briggs SP, Firtel RA. Kölsch V, et al. Among authors: kortholt a. Mol Biol Cell. 2013 Jan;24(2):100-14. doi: 10.1091/mbc.E12-04-0271. Epub 2012 Nov 7. Mol Biol Cell. 2013. PMID: 23135995 Free PMC article.

6

GxcC connects Rap and Rac signaling during Dictyostelium development.

Plak K, Veltman D, Fusetti F, Beeksma J, Rivero F, Van Haastert PJ, Kortholt A. Plak K, et al. Among authors: kortholt a. BMC Cell Biol. 2013 Jan 30;14:6. doi: 10.1186/1471-2121-14-6. BMC Cell Biol. 2013. PMID: 23363311 Free PMC article.

7

Dictyostelium Ric8 is a nonreceptor guanine exchange factor for heterotrimeric G proteins and is important for development and chemotaxis.

Kataria R, Xu X, Fusetti F, Keizer-Gunnink I, Jin T, van Haastert PJ, Kortholt A. Kataria R, et al. Among authors: kortholt a. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6424-9. doi: 10.1073/pnas.1301851110. Epub 2013 Apr 1. Proc Natl Acad Sci U S A. 2013. PMID: 23576747 Free PMC article.

8

Rap1-dependent pathways coordinate cytokinesis in Dictyostelium.

Plak K, Keizer-Gunnink I, van Haastert PJ, Kortholt A. Plak K, et al. Among authors: kortholt a. Mol Biol Cell. 2014 Dec 15;25(25):4195-204. doi: 10.1091/mbc.E14-08-1285. Epub 2014 Oct 8. Mol Biol Cell. 2014. PMID: 25298405 Free PMC article.

9

Homer3 regulates the establishment of neutrophil polarity.

Wu J, Pipathsouk A, Keizer-Gunnink A, Fusetti F, Alkema W, Liu S, Altschuler S, Wu L, Kortholt A, Weiner OD. Wu J, et al. Among authors: kortholt a. Mol Biol Cell. 2015 May 1;26(9):1629-39. doi: 10.1091/mbc.E14-07-1197. Epub 2015 Mar 4. Mol Biol Cell. 2015. PMID: 25739453 Free PMC article.

10

Function and Regulation of Heterotrimeric G Proteins during Chemotaxis.

Kamp ME, Liu Y, Kortholt A. Kamp ME, et al. Among authors: kortholt a. Int J Mol Sci. 2016 Jan 14;17(1):90. doi: 10.3390/ijms17010090. Int J Mol Sci. 2016. PMID: 26784171 Free PMC article. Review.

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