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Immunization with DISC1 protein in an animal model of ADHD influences behavior and excitatory amino acids in prefrontal cortex and striatum.
Ruocco LA, Treno C, Gironi Carnevale UA, Arra C, Boatto G, Pagano C, Tino A, Nieddu M, Michel M, Prikulis I, Carboni E, de Souza Silva MA, Huston JP, Sadile AG, Korth C. Ruocco LA, et al. Among authors: korth c. Amino Acids. 2015 Mar;47(3):637-50. doi: 10.1007/s00726-014-1897-6. Epub 2015 Jan 17. Amino Acids. 2015. PMID: 25595600
Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.
Trossbach SV, Bader V, Hecher L, Pum ME, Masoud ST, Prikulis I, Schäble S, de Souza Silva MA, Su P, Boulat B, Chwiesko C, Poschmann G, Stühler K, Lohr KM, Stout KA, Oskamp A, Godsave SF, Müller-Schiffmann A, Bilzer T, Steiner H, Peters PJ, Bauer A, Sauvage M, Ramsey AJ, Miller GW, Liu F, Seeman P, Brandon NJ, Huston JP, Korth C. Trossbach SV, et al. Among authors: korth c. Mol Psychiatry. 2016 Nov;21(11):1561-1572. doi: 10.1038/mp.2015.194. Epub 2016 Jan 12. Mol Psychiatry. 2016. PMID: 26754951 Free PMC article.
Disrupted-in-Schizophrenia 1 (DISC1) Overexpression and Juvenile Immune Activation Cause Sex-Specific Schizophrenia-Related Psychopathology in Rats.
Uzuneser TC, Speidel J, Kogias G, Wang AL, de Souza Silva MA, Huston JP, Zoicas I, von Hörsten S, Kornhuber J, Korth C, Müller CP. Uzuneser TC, et al. Among authors: korth c. Front Psychiatry. 2019 Apr 9;10:222. doi: 10.3389/fpsyt.2019.00222. eCollection 2019. Front Psychiatry. 2019. PMID: 31057438 Free PMC article.
Quantitative Proteomics of Synaptosomal Fractions in a Rat Overexpressing Human DISC1 Gene Indicates Profound Synaptic Dysregulation in the Dorsal Striatum.
Sialana FJ, Wang AL, Fazari B, Kristofova M, Smidak R, Trossbach SV, Korth C, Huston JP, de Souza Silva MA, Lubec G. Sialana FJ, et al. Among authors: korth c. Front Mol Neurosci. 2018 Feb 6;11:26. doi: 10.3389/fnmol.2018.00026. eCollection 2018. Front Mol Neurosci. 2018. PMID: 29467617 Free PMC article.
156 results