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Juvenile Arthritis Patients Suffering from Chronic Inflammation Have Increased Activity of Both IDO and GTP-CH1 Pathways But Decreased BH4 Efficacy: Implications for Well-Being, Including Fatigue, Cognitive Impairment, Anxiety, and Depression.
Korte-Bouws GAH, Albers E, Voskamp M, Hendriksen H, de Leeuw LR, Güntürkün O, de Roock S, Vastert SJ, Korte SM. Korte-Bouws GAH, et al. Pharmaceuticals (Basel). 2019 Jan 8;12(1):9. doi: 10.3390/ph12010009. Pharmaceuticals (Basel). 2019. PMID: 30625990 Free PMC article.
The 5-HT1A/1B-receptor agonist eltoprazine increases both catecholamine release in the prefrontal cortex and dopamine release in the nucleus accumbens and decreases motivation for reward and "waiting" impulsivity, but increases "stopping" impulsivity.
Korte SM, Prins J, Van den Bergh FS, Oosting RS, Dupree R, Korte-Bouws GA, Westphal KG, Olivier B, Denys DA, Garland A, Güntürkün O. Korte SM, et al. Eur J Pharmacol. 2017 Jan 5;794:257-269. doi: 10.1016/j.ejphar.2016.11.024. Epub 2016 Nov 17. Eur J Pharmacol. 2017. PMID: 27866999
35 results