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Acetyl-CoA carboxylase inhibition disrupts metabolic reprogramming during hepatic stellate cell activation.
Bates J, Vijayakumar A, Ghoshal S, Marchand B, Yi S, Kornyeyev D, Zagorska A, Hollenback D, Walker K, Liu K, Pendem S, Newstrom D, Brockett R, Mikaelian I, Kusam S, Ramirez R, Lopez D, Li L, Fuchs BC, Breckenridge DG. Bates J, et al. Among authors: kornyeyev d. J Hepatol. 2020 Oct;73(4):896-905. doi: 10.1016/j.jhep.2020.04.037. Epub 2020 May 4. J Hepatol. 2020. PMID: 32376414 Free article.
Characterization of the liver immune microenvironment in liver biopsies from patients with chronic HBV infection.
van Buuren N, Ramirez R, Turner S, Chen D, Suri V, Aggarwal A, Moon C, Kim S, Kornyeyev D, Bui N, Bhardwaj N, Chan HL, Marcellin P, Buti M, Wallin J, Gaggar A, Fletcher SP, Diehl L, Li L, Mo H, Feierbach B. van Buuren N, et al. Among authors: kornyeyev d. JHEP Rep. 2021 Oct 24;4(1):100388. doi: 10.1016/j.jhepr.2021.100388. eCollection 2022 Jan. JHEP Rep. 2021. PMID: 34950863 Free PMC article.
Off-Target In Vitro Profiling Demonstrates that Remdesivir Is a Highly Selective Antiviral Agent.
Xu Y, Barauskas O, Kim C, Babusis D, Murakami E, Kornyeyev D, Lee G, Stepan G, Perron M, Bannister R, Schultz BE, Sakowicz R, Porter D, Cihlar T, Feng JY. Xu Y, et al. Among authors: kornyeyev d. Antimicrob Agents Chemother. 2021 Jan 20;65(2):e02237-20. doi: 10.1128/AAC.02237-20. Print 2021 Jan 20. Antimicrob Agents Chemother. 2021. PMID: 33229429 Free PMC article.
Establishment and Characterization of an HBV Viral Spread and Infectious System following Long-Term Passage of an HBV Clinical Isolate in the Primary Human Hepatocyte and Fibroblast Coculture System.
Liu Y, Kornyeyev D, May L, Han D, Aeschbacher T, Chang S, Martin R, Mo H, Feierbach B. Liu Y, et al. Among authors: kornyeyev d. J Virol. 2022 Sep 28;96(18):e0084922. doi: 10.1128/jvi.00849-22. Epub 2022 Aug 29. J Virol. 2022. PMID: 36037476 Free PMC article.
Smc5/6 silences episomal transcription by a three-step function.
Abdul F, Diman A, Baechler B, Ramakrishnan D, Kornyeyev D, Beran RK, Fletcher SP, Strubin M. Abdul F, et al. Among authors: kornyeyev d. Nat Struct Mol Biol. 2022 Sep;29(9):922-931. doi: 10.1038/s41594-022-00829-0. Epub 2022 Sep 12. Nat Struct Mol Biol. 2022. PMID: 36097294
Discovery of Potent and Selective MTH1 Inhibitors for Oncology: Enabling Rapid Target (In)Validation.
Farand J, Kropf JE, Blomgren P, Xu J, Schmitt AC, Newby ZE, Wang T, Murakami E, Barauskas O, Sudhamsu J, Feng JY, Niedziela-Majka A, Schultz BE, Schwartz K, Viatchenko-Karpinski S, Kornyeyev D, Kashishian A, Fan P, Chen X, Lansdon EB, Ports MO, Currie KS, Watkins WJ, Notte GT. Farand J, et al. Among authors: kornyeyev d. ACS Med Chem Lett. 2019 Nov 19;11(3):358-364. doi: 10.1021/acsmedchemlett.9b00420. eCollection 2020 Mar 12. ACS Med Chem Lett. 2019. PMID: 32184970 Free PMC article.
31 results