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Carbonic anhydrase inhibitors. Inhibition of the cytosolic human isozymes I and II, and the transmembrane, tumor-associated isozymes IX and XII with substituted aromatic sulfonamides activatable in hypoxic tumors.
Saczewski F, Sławiński J, Kornicka A, Brzozowski Z, Pomarnacka E, Innocenti A, Scozzafava A, Supuran CT. Saczewski F, et al. Among authors: kornicka a. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4846-51. doi: 10.1016/j.bmcl.2006.06.064. Epub 2006 Jun 30. Bioorg Med Chem Lett. 2006. PMID: 16809036
Carbonic anhydrase inhibitors. Selective inhibition of human tumor-associated isozymes IX and XII and cytosolic isozymes I and II with some substituted-2-mercapto-benzenesulfonamides.
Saczewski F, Innocenti A, Brzozowski Z, Slawiński J, Pomarnacka E, Kornicka A, Scozzafava A, Supuran CT. Saczewski F, et al. Among authors: kornicka a. J Enzyme Inhib Med Chem. 2006 Oct;21(5):563-8. doi: 10.1080/14756360600648146. J Enzyme Inhib Med Chem. 2006. PMID: 17194028
Carbonic anhydrase inhibitors: inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides.
Saczewski F, Innocenti A, Sławiński J, Kornicka A, Brzozowski Z, Pomarnacka E, Scozzafava A, Temperini C, Supuran CT. Saczewski F, et al. Among authors: kornicka a. Bioorg Med Chem. 2008 Apr 1;16(7):3933-40. doi: 10.1016/j.bmc.2008.01.034. Epub 2008 Jan 26. Bioorg Med Chem. 2008. PMID: 18242998
Synthesis, cytotoxicity testing, and structure-activity relationships of novel 6-chloro-7-(4-phenylimino-4H-3,1-benzoxazin-2-yl)-3-(substituted)-1,4,2-benzodithiazine 1,1-dioxides.
Pomarnacka E, Kornicka A, Kuchnio A, Heinrichs M, Grünert R, Gdaniec M, Bednarski PJ. Pomarnacka E, et al. Among authors: kornicka a. Arch Pharm (Weinheim). 2011 Jul;344(7):431-41. doi: 10.1002/ardp.201000183. Epub 2011 May 25. Arch Pharm (Weinheim). 2011. PMID: 21618270 Free PMC article.
32 results