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Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells.
Nakano I, Masterman-Smith M, Saigusa K, Paucar AA, Horvath S, Shoemaker L, Watanabe M, Negro A, Bajpai R, Howes A, Lelievre V, Waschek JA, Lazareff JA, Freije WA, Liau LM, Gilbertson RJ, Cloughesy TF, Geschwind DH, Nelson SF, Mischel PS, Terskikh AV, Kornblum HI. Nakano I, et al. Among authors: kornblum hi. J Neurosci Res. 2008 Jan;86(1):48-60. doi: 10.1002/jnr.21471. J Neurosci Res. 2008. PMID: 17722061
A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens.
Sun J, Masterman-Smith MD, Graham NA, Jiao J, Mottahedeh J, Laks DR, Ohashi M, DeJesus J, Kamei K, Lee KB, Wang H, Yu ZT, Lu YT, Hou S, Li K, Liu M, Zhang N, Wang S, Angenieux B, Panosyan E, Samuels ER, Park J, Williams D, Konkankit V, Nathanson D, van Dam RM, Phelps ME, Wu H, Liau LM, Mischel PS, Lazareff JA, Kornblum HI, Yong WH, Graeber TG, Tseng HR. Sun J, et al. Among authors: kornblum hi. Cancer Res. 2010 Aug 1;70(15):6128-38. doi: 10.1158/0008-5472.CAN-10-0076. Epub 2010 Jul 14. Cancer Res. 2010. PMID: 20631065 Free PMC article.
Autocrine endothelin-3/endothelin receptor B signaling maintains cellular and molecular properties of glioblastoma stem cells.
Liu Y, Ye F, Yamada K, Tso JL, Zhang Y, Nguyen DH, Dong Q, Soto H, Choe J, Dembo A, Wheeler H, Eskin A, Schmid I, Yong WH, Mischel PS, Cloughesy TF, Kornblum HI, Nelson SF, Liau LM, Tso CL. Liu Y, et al. Among authors: kornblum hi. Mol Cancer Res. 2011 Dec;9(12):1668-85. doi: 10.1158/1541-7786.MCR-10-0563. Epub 2011 Oct 19. Mol Cancer Res. 2011. PMID: 22013079 Free PMC article.
A molecular cascade modulates MAP1B and confers resistance to mTOR inhibition in human glioblastoma.
Laks DR, Oses-Prieto JA, Alvarado AG, Nakashima J, Chand S, Azzam DB, Gholkar AA, Sperry J, Ludwig K, Condro MC, Nazarian S, Cardenas A, Shih MYS, Damoiseaux R, France B, Orozco N, Visnyei K, Crisman TJ, Gao F, Torres JZ, Coppola G, Burlingame AL, Kornblum HI. Laks DR, et al. Among authors: kornblum hi. Neuro Oncol. 2018 May 18;20(6):764-775. doi: 10.1093/neuonc/nox215. Neuro Oncol. 2018. PMID: 29136244 Free PMC article.
Pathway-based approach reveals differential sensitivity to E2F1 inhibition in glioblastoma.
Alvarado AG, Tessema K, Muthukrishnan SD, Sober M, Kawaguchi R, Laks DR, Bhaduri A, Swarup V, Nathanson DA, Geschwind DH, Goldman SA, Kornblum HI. Alvarado AG, et al. Among authors: kornblum hi. Cancer Res Commun. 2022 Sep;2(9):1049-1060. doi: 10.1158/2767-9764.crc-22-0003. Epub 2022 Sep 22. Cancer Res Commun. 2022. PMID: 36213002 Free PMC article.
167 results