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Unique Gene Expression Signatures in the Intestinal Mucosa and Organoids Derived from Germ-Free and Monoassociated Mice.
Janeckova L, Kostovcikova K, Svec J, Stastna M, Strnad H, Kolar M, Hudcovic T, Stancikova J, Tureckova J, Baloghova N, Sloncova E, Galuskova K, Tlaskalova-Hogenova H, Korinek V. Janeckova L, et al. Among authors: korinek v. Int J Mol Sci. 2019 Mar 29;20(7):1581. doi: 10.3390/ijms20071581. Int J Mol Sci. 2019. PMID: 30934845 Free PMC article.
Generation of two modified mouse alleles of the Hic1 tumor suppressor gene.
Pospichalova V, Tureckova J, Fafilek B, Vojtechova M, Krausova M, Lukas J, Sloncova E, Takacova S, Divoky V, Leprince D, Plachy J, Korinek V. Pospichalova V, et al. Among authors: korinek v. Genesis. 2011 Mar;49(3):142-51. doi: 10.1002/dvg.20719. Genesis. 2011. PMID: 21309068
Troy, a tumor necrosis factor receptor family member, interacts with lgr5 to inhibit wnt signaling in intestinal stem cells.
Fafilek B, Krausova M, Vojtechova M, Pospichalova V, Tumova L, Sloncova E, Huranova M, Stancikova J, Hlavata A, Svec J, Sedlacek R, Luksan O, Oliverius M, Voska L, Jirsa M, Paces J, Kolar M, Krivjanska M, Klimesova K, Tlaskalova-Hogenova H, Korinek V. Fafilek B, et al. Among authors: korinek v. Gastroenterology. 2013 Feb;144(2):381-391. doi: 10.1053/j.gastro.2012.10.048. Epub 2012 Nov 7. Gastroenterology. 2013. PMID: 23142137
Monensin inhibits canonical Wnt signaling in human colorectal cancer cells and suppresses tumor growth in multiple intestinal neoplasia mice.
Tumova L, Pombinho AR, Vojtechova M, Stancikova J, Gradl D, Krausova M, Sloncova E, Horazna M, Kriz V, Machonova O, Jindrich J, Zdrahal Z, Bartunek P, Korinek V. Tumova L, et al. Among authors: korinek v. Mol Cancer Ther. 2014 Apr;13(4):812-22. doi: 10.1158/1535-7163.MCT-13-0625. Epub 2014 Feb 19. Mol Cancer Ther. 2014. PMID: 24552772
NKD1 marks intestinal and liver tumors linked to aberrant Wnt signaling.
Stancikova J, Krausova M, Kolar M, Fafilek B, Svec J, Sedlacek R, Neroldova M, Dobes J, Horazna M, Janeckova L, Vojtechova M, Oliverius M, Jirsa M, Korinek V. Stancikova J, et al. Among authors: korinek v. Cell Signal. 2015 Feb;27(2):245-56. doi: 10.1016/j.cellsig.2014.11.008. Epub 2014 Nov 14. Cell Signal. 2015. PMID: 25446263 Free article.
HIC1 Tumor Suppressor Loss Potentiates TLR2/NF-κB Signaling and Promotes Tissue Damage-Associated Tumorigenesis.
Janeckova L, Pospichalova V, Fafilek B, Vojtechova M, Tureckova J, Dobes J, Dubuissez M, Leprince D, Baloghova N, Horazna M, Hlavata A, Stancikova J, Sloncova E, Galuskova K, Strnad H, Korinek V. Janeckova L, et al. Among authors: korinek v. Mol Cancer Res. 2015 Jul;13(7):1139-48. doi: 10.1158/1541-7786.MCR-15-0033. Epub 2015 May 1. Mol Cancer Res. 2015. PMID: 25934696
MMP-19 deficiency causes aggravation of colitis due to defects in innate immune cell function.
Brauer R, Tureckova J, Kanchev I, Khoylou M, Skarda J, Prochazka J, Spoutil F, Beck IM, Zbodakova O, Kasparek P, Korinek V, Chalupsky K, Karhu T, Herzig KH, Hajduch M, Gregor M, Sedlacek R. Brauer R, et al. Among authors: korinek v. Mucosal Immunol. 2016 Jul;9(4):974-85. doi: 10.1038/mi.2015.117. Epub 2015 Nov 11. Mucosal Immunol. 2016. PMID: 26555704 Free article.
Wnt Signaling Inhibition Deprives Small Intestinal Stem Cells of Clonogenic Capacity.
Janeckova L, Fafilek B, Krausova M, Horazna M, Vojtechova M, Alberich-Jorda M, Sloncova E, Galuskova K, Sedlacek R, Anderova M, Korinek V. Janeckova L, et al. Among authors: korinek v. Genesis. 2016 Mar;54(3):101-14. doi: 10.1002/dvg.22922. Epub 2016 Feb 16. Genesis. 2016. PMID: 26864984 Free PMC article.
HIC1 Expression Distinguishes Intestinal Carcinomas Sensitive to Chemotherapy.
Janeckova L, Kolar M, Svec J, Lanikova L, Pospichalova V, Baloghova N, Vojtechova M, Sloncova E, Strnad H, Korinek V. Janeckova L, et al. Among authors: korinek v. Transl Oncol. 2016 Apr;9(2):99-107. doi: 10.1016/j.tranon.2016.01.005. Epub 2016 Mar 4. Transl Oncol. 2016. PMID: 27084425 Free PMC article.
78 results